132659-98-4Relevant articles and documents
Mechanism driven trans stereospecificity in the Pictet-Spengler reaction. Stereospecific formation of trans-1,2,3-trisubstituted-tetrahydro β-carbolines by condensation of N(b)-diphenylmethyl tryptophan isopropyl esters with aldehydes
Czerwinski,Deng,Cook
, p. 4721 - 4724 (2007/10/02)
Stereoelectronic control in the Pictet-Spengler condensation of N(b)-alkylsubstituted tryptophan alkyl esters has been employed to promote 100% stereoselectivity in this process. The reaction of N(b)-diphenylmethyl tryptophan isopropyl ester 8 with acetal