1327277-94-0

Basic information

• Product Name: N-((R)-2-hydroxy-1-phenylethyl)-3,3-dimethyl-pentanamide
• Synonyms: N-((R)-2-hydroxy-1-phenylethyl)-3,3-dimethyl-pentanamide
• CAS NO: 1327277-94-0
• Molecular Weight: 249.353
• Mol File: 1327277-94-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-((R)-2-hydroxy-1-phenylethyl)-3,3-dimethyl-pentanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-((R)-2-hydroxy-1-phenylethyl)-3,3-dimethyl-pentanamide(1327277-94-0)
• EPA Substance Registry System: N-((R)-2-hydroxy-1-phenylethyl)-3,3-dimethyl-pentanamide(1327277-94-0)

Safety Data

• Hazardous Substances Data: 1327277-94-0(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 79097-84-0 3,3-dimethylpentanoyl chloride 
• 3177-74-0 3,3-dimethylpentanoic acid 

Downstream Products

• 1327277-99-5 (R)-4,5-dihydro-2-(2,2-dimethylbutyl)-4-phenyloxazole 
• 1327278-28-3 C₁₆H₂₃N₅O₇ 
• 1327278-27-2 C₁₆H₂₃N₅O₇ 
• 1327278-11-4 (3S,5R)-3-tert-pentyl-5-phenyl-morpholin-2-one 
• 1327278-06-7 (R)-3-tert-pentyl-5,6-dihydro-5-phenyl-1,4-oxazin-2-one 

Relevant articles and documents

Preparation of α-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations

The range and scope of the oxidative oxazoline-oxazinone rearrangement-hydrogenation sequence (OOOH)-a short, direct asymmetric synthesis of α-amino acids from carboxylic acids-was explored. The highest yet reported diastereoselectivity for hydrogenation of the oxazinone C=N bond (d.r.=>80:1) is disclosed and rationalized with the aid of ab initio molecular calculations.