132741-31-2 Usage
Description
3,5-Difluoromandelic acid, also known as α-hydroxy-3,5-difluorophenylacetic acid, is a white powdery compound that undergoes optical resolution in the presence of (1R,2R)-(-)-pseudoephedrine in isopropanol to yield the (S)-form. This organic compound is characterized by the presence of two fluorine atoms at the 3rd and 5th positions of the benzene ring, attached to a carboxylic acid and an alcohol functional group.
Uses
Used in Pharmaceutical Industry:
3,5-Difluoromandelic acid is used as an intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique chemical structure allows it to be a versatile building block in the development of new drugs, particularly those targeting specific enzymes or receptors in the body.
Used in Chemical Synthesis:
In the field of organic chemistry, 3,5-Difluoromandelic acid is used as a key building block for the creation of more complex molecules with potential applications in various industries, such as agrochemicals, materials science, and specialty chemicals. Its fluorinated structure can impart unique properties to the final products, making it valuable for research and development purposes.
Used in Research and Development:
3,5-Difluoromandelic acid is utilized in research and development for the study of its chemical properties, reactivity, and potential applications in various fields. Its optical resolution into the (S)-form provides opportunities for investigating the effects of stereochemistry on biological activity and other properties, which can be crucial in the design of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 132741-31-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,7,4 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 132741-31:
(8*1)+(7*3)+(6*2)+(5*7)+(4*4)+(3*1)+(2*3)+(1*1)=102
102 % 10 = 2
So 132741-31-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F2O3/c9-5-1-4(2-6(10)3-5)7(11)8(12)13/h1-3,7,11H,(H,12,13)/p-1/t7-/m1/s1
132741-31-2Relevant articles and documents
Kinetic resolution of mandelate esters via stereoselective acylation catalyzed by lipase PS-30
Chen, Peiran,Yang, Wenhong
, p. 2290 - 2294 (2014/04/17)
By using lipase PS-30 as catalyst, the kinetic resolution of a series of racemic mandelate esters has been achieved via stereoselective acylation. The value of kinetic enantiomeric ratio (E) reached up to 197.5. Substituent effect is briefly discussed.
