13280-00-7

Basic information

• Product Name: 3-chloropentan-2-one
• Synonyms: 3-chloropentan-2-one;2-Pentanone, 3-chloro- (6CI,7CI,8CI,9CI)
• CAS NO: 13280-00-7
• Molecular Formula: C₅H₉ClO
• Molecular Weight: 120.57736
• EINECS: 236-282-9
• Product Categories: ACETYLGROUP
• Mol File: 13280-00-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 135.2°Cat760mmHg
• Flash Point: 50.5°C
• Appearance: /
• Density: 1.005g/cm³
• Vapor Pressure: 7.8mmHg at 25°C
• Refractive Index: 1.415
• CAS DataBase Reference: 3-chloropentan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloropentan-2-one(13280-00-7)
• EPA Substance Registry System: 3-chloropentan-2-one(13280-00-7)

Safety Data

• Hazardous Substances Data: 13280-00-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H9ClO/c1-3-5(6)4(2)7/h5H,3H2,1-2H3

Upstream product

• 98486-25-0 3-chloro-2-hydroxy-2-methyl-valeraldehyde 
• 130000-37-2 2-ethyl-2-chloro-acetoacetic acid ethyl ester 
• 107-87-9 2-Pentanone 
• 75-19-4 cyclopropane 
• 75-36-5 acetyl chloride 
• 130000-33-8 methyl 2-chloro-2-ethyl-3-oxobutanoate 
• 625-35-4 trans-chrotonyl chloride 
• 917-65-7 methylaluminum dichloride 
• 7791-25-5 sulfuryl dichloride 
• 71-43-2 benzene 
• 7782-50-5 chlorine 
• 7647-01-0 hydrogenchloride 
• 64-19-7 acetic acid 
• 51756-08-2 methyl 2-ethyl-3-oxobutanoate 

Downstream Products

• 31883-01-9 4-methyl-5-ethylthiazole 
• 17649-00-2 3--pentan-2-on 
• 29025-26-1 3-(2-Methoxy-phenoxy)-pentan-2-one 
• 1026014-05-0 1-(1-ethyl-2-oxo-propyl)-piperidin-2-one 
• 600-14-6 2,3-Pentanedione 
• 69736-37-4 5-Ethyl-4-ethynyl-2,2,4-trimethyl-[1,3]dioxolane 
• 1311386-58-9 4-chloro-3-methyl-1-phenylhex-1-yn-3-ol 
• 6116-76-3 3-ethyl-2-methyl-4-oxo-1H-4,5,6,7-tetrahydroindole 

Relevant articles and documents

Novel Regioselective Chlorination of Aliphatic Ketones via Mono-organothallium(III) Derivates

Room temperature reaction of simple aliphatic ketones with an aqueous solution of TiCl3 leads to mono-oxoalkylthalium(III) derivatives followed by formation of selectively α-monochlorinated ketones.

PROCESS FOR PREPARATION OF MOLINDONE

The present invention provides process for preparation of molindone (I) comprising: a) reacting compound with cyclohexane-1,3-dione to form 2-(2-oxopentan-3-yl)cyclohexane-1,3-dione wherein X is Cl, Br or I, b) cyclizing 2-(2-oxopentan-3-yl)cyclohexane-1,

CYCLOBUTENEDIONE DERIVATIVES

The present invention relates to compounds of the formula (I): to pharmaceutically acceptable salts therefore and to pharmaceutically acceptable solvates of said compounds and salts, wherein the substituents are defined herein; to compositions containing such compounds; and to the uses of such compounds in the treatment of various diseases, particularly inflammatory conditions.

A Convenient Synthesis of 3-Chloro-2-alkanones

3-Chloro-2-alkanones were regiospecifically synthesized from methyl 2-alkyl-3-oxobutanoates by chlorination to afford methyl 2-alkyl-2-chloro-3-oxobutanoates followed by demethoxycarbonylation in acid medium.