132836-68-1

Basic information

• Product Name: (S)-3-(tert-butoxycarbonyl)-4-benzyl-2-oxazolidinone
• Synonyms: (S)-3-(tert-butoxycarbonyl)-4-benzyl-2-oxazolidinone
• CAS NO: 132836-68-1
• Molecular Weight: 277.32
• Mol File: 132836-68-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-3-(tert-butoxycarbonyl)-4-benzyl-2-oxazolidinone(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-(tert-butoxycarbonyl)-4-benzyl-2-oxazolidinone(132836-68-1)
• EPA Substance Registry System: (S)-3-(tert-butoxycarbonyl)-4-benzyl-2-oxazolidinone(132836-68-1)

Safety Data

• Hazardous Substances Data: 132836-68-1(Hazardous Substances Data)

Upstream product

• 124-38-9 carbon dioxide 
• 141403-49-8 (2S)-2-[N-(tert-butoxycarbonyl)amino]-3-phenyl-O-(4-methylphenylsulfonyl)propan-1-ol 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 

Relevant articles and documents

Substrate Acidities and Conversion Times for Reactions of Amides With Di-tert-butyl Dicarbonate

The conversion time for 4-dimethylaminopyridine catalyzed reaction of amides with tert-butyl dicarbonate varies dramatically with substrate acidity.The pKa's in DMSO of some amides are determined to support correlation of reactivity with substr

Simple and efficient N-acylation reactions of chiral oxazolidinone auxiliaries

A simplified procedure for the N-acylation of oxazolidin-2-one chiral auxiliaries has been developed. The acylations occur at room temperature in the presence of triethylamine and catalytic quantities of 4-(N,N-dimethylamino)pyridine, thereby eliminating the necessity for a strong base such as butyllithium. Acylations with both symmetrical and mixed anhydrides, as well as acid chlorides, occur with a wide variety of oxazolidinone auxiliaries.