132858-47-0 Usage
Description
1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one, commonly known as Paeonol, is a chemical compound derived from the natural product paeony root. It is a secondary metabolite found in various plants and is recognized for its diverse biological activities, which include anti-inflammatory, antioxidant, and anti-cancer properties. Paeonol has been extensively studied for its potential therapeutic effects, particularly in the treatment of inflammatory and immune-related conditions. It is also being investigated for its potential use in skincare products due to its antioxidant and anti-aging properties. Furthermore, paeonol has shown promise as a potential treatment for neurodegenerative diseases, such as Alzheimer's and Parkinson's, due to its neuroprotective effects. Overall, paeonol has demonstrated a wide range of pharmacological activities and potential therapeutic applications in the fields of medicine and skincare.
Uses
Used in Pharmaceutical Applications:
1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one is used as an anti-inflammatory agent for its ability to alleviate inflammatory and immune-related conditions. Its anti-inflammatory properties make it a promising candidate for the treatment of various diseases and disorders.
Used in Skincare Applications:
In the skincare industry, 1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one is used as an antioxidant and anti-aging ingredient for its potential to protect the skin from oxidative stress and promote a youthful appearance.
Used in Neurodegenerative Disease Treatment:
1-(3,4-dimethoxyphenyl)-3-methylbutan-1-one is used as a neuroprotective agent for its potential to treat neurodegenerative diseases such as Alzheimer's and Parkinson's, due to its ability to protect neurons and slow down the progression of these conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 132858-47-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,8,5 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 132858-47:
(8*1)+(7*3)+(6*2)+(5*8)+(4*5)+(3*8)+(2*4)+(1*7)=140
140 % 10 = 0
So 132858-47-0 is a valid CAS Registry Number.
132858-47-0Relevant articles and documents
DIMETHOXYPHENYL SUBSTITUTED INDOLE COMPOUNDS AS TLR7, TLR8 OR TLR9 INHIBITORS
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Page/Page column 197; 198, (2018/03/28)
Disclosed are compounds of Formula (I) or a salt thereof, wherein R1, R3, R4, R5, m, and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
SUBSTITUTED 6,7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE10A)
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Page/Page column 62; 63; 65, (2014/05/24)
The invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein R', R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.
Conception, characterization and correlation of new marine odorants
Kraft, Philip,Eichenberger, Walter
, p. 3735 - 3743 (2007/10/03)
Via a synthetic sequence consisting of PPA-mediated Friedel-Crafts acylation of veratrol (8), Clemmensen reduction, demethylation with TMSI, Williamson ether synthesis employing 3-chloro-2-(chloromethyl)prop-1-ene and in-situ ruthenium tetroxide oxidation, numerous substituted benzo[b][1,4]dioxepinones 15-27 and 2,3-dihydro-1H-5,9-di-oxacyclohepta[f]indenones 7, 13 and 14 were prepared to study their odor-structure correlation. In the course of these studies, we discovered the extremely powerful new marine odorant 7-(3′ -methylbutyl)benzo[b][1,4]dioxepin-3-one (16). On the basis of the measured odor threshold data, an olfactophore model was constructed that rationalizes the observed odor intensities, and indicates an aliphatic hydrophobe at a distance of 6.3 A from the centre of the aromatic-ring binding site. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.
