132911-62-7Relevant articles and documents
Highly enantioselective mukaiyama aldol reactions catalyzed by a chiral oxazaborolidinium ion: Total synthesis of (-)-inthomycin C
Senapati, Bidyut Kumar,Gao, Lizhu,Lee, Sung Il,Hwang, Geum-Sook,Ryu, Do Hyun
supporting information; experimental part, p. 5088 - 5091 (2011/01/05)
A cationic oxazaborolidinium-catalyzed asymmetric Mukaiyama aldol reaction of (1-methoxy-2-methyl-propenyloxy)-trimethylsilane with various aldehydes including α,β-disubstituted acroleins has been developed in high yields and enantioselectivities. The synthetic utility of this methodology was demonstrated in the first short synthesis of naturally occurring inthomycin C in high enantiopurity.
