1329496-43-6

Basic information

• Product Name: Irbesartan-d7
• Synonyms: Irbesartan-d7;2-Butyl-3-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1,3-diazaspiro[4.4]non-1-en-4-one-d7;Irbesartan-d7 (Discontinued, see I751007);2-(2,2,3,3,4,4,4-heptadeuteriobutyl)-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one
• CAS NO: 1329496-43-6
• Molecular Formula: C25H27N6O
• Molecular Weight: 427.52148
• Product Categories: Inhibitors;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Inhibitors, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1329496-43-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform, Methanol
• CAS DataBase Reference: Irbesartan-d7(CAS DataBase Reference)
• NIST Chemistry Reference: Irbesartan-d7(1329496-43-6)
• EPA Substance Registry System: Irbesartan-d7(1329496-43-6)

Safety Data

• Hazardous Substances Data: 1329496-43-6(Hazardous Substances Data)

Usage

Description

Irbesartan-d7 is a deuterated analog of the angiotensin II type 1 (AII1)-receptor antagonist, Irbesartan. It is a pale yellow solid and is commonly used as a labeled compound in various applications.

Uses

Used in Pharmaceutical Industry:
Irbesartan-d7 is used as a labeled compound for the development and optimization of analytical methods and techniques in the pharmaceutical industry. Its deuterated nature allows for improved sensitivity and selectivity in mass spectrometry and other analytical techniques, facilitating the detection and quantification of Irbesartan and its metabolites.
Used in Research and Development:
Irbesartan-d7 is used as a research tool for studying the pharmacokinetics, metabolism, and mechanism of action of Irbesartan. Its deuterated form provides a stable and non-radioactive alternative to radiolabeled compounds, making it suitable for use in preclinical and clinical studies.
Used in Quality Control and Assay Development:
Irbesartan-d7 is used as an internal standard or reference material in the development and validation of quality control assays and methods. Its deuterated nature ensures accurate quantification and reliable results, helping to maintain the quality and consistency of Irbesartan-containing products.
Used in Drug Metabolism and Pharmacokinetic Studies:
Irbesartan-d7 is used as a stable isotope tracer in drug metabolism and pharmacokinetic studies. Its incorporation into biological samples allows for the tracking and analysis of Irbesartan's metabolic pathways, providing valuable insights into its pharmacological properties and potential drug-drug interactions.