132960-13-5

Basic information

• Product Name: 2-Propynamide, N-methoxy-N-methyl-3-phenyl-
• CAS NO: 132960-13-5
• Molecular Formula: C11H11NO2
• Molecular Weight: 189.214
• Mol File: 132960-13-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: 2-Propynamide, N-methoxy-N-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propynamide, N-methoxy-N-methyl-3-phenyl-(132960-13-5)
• EPA Substance Registry System: 2-Propynamide, N-methoxy-N-methyl-3-phenyl-(132960-13-5)

Safety Data

• Hazardous Substances Data: 132960-13-5(Hazardous Substances Data)

Upstream product

• 123707-26-6 N,N'-dimethoxy-N,N'-dimethyl urea 
• 536-74-3 phenylacetylene 
• 30289-28-2 N-methoxy-N-methylcarbamoyl chloride 
• 3757-88-8 tributylstannylethynylbenzene 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 637-44-5 phenylpropyolic acid 
• 123707-27-7 N-methoxyurea-N,N',N'-trimethylurea 
• 201230-82-2 carbon monoxide 
• 932-88-7 1-iodo-2-phenylethyne 
• 1117-97-1 N,0-dimethylhydroxylamine 
• 7342-02-1 3-phenylpropynoic acid phenylamide 

Downstream Products

• 105850-88-2 (cyclohex-1-en-1-ylbuta-1,3-diyn-1-yl)benzene 
• 1430234-54-0 7-((4-methoxybenzyl)oxy)-1-phenylhepta-1,4-diyn-3-one 
• 1430234-47-1 1-mesityl-5-phenylpenta-1,4-diyn-3-one 
• 1430234-52-8 1-(naphthalen-1-yl)-5-phenylpenta-1,4-diyn-3-one 
• 1430234-48-2 1-(cyclohex-1-en-1-yl)-5-phenylpenta-1,4-diyn-3-one 
• 109034-34-6 1-(4-methoxyphenyl)-5-phenyl-1,4-pentadiyn-3-one 
• 1430234-50-6 1-(4-chlorophenyl)-5-phenylpenta-1,4-diyn-3-one 
• 1430234-94-8 1-(4-bromophenyl)-5-phenylpenta-1,4-diyn-3-one 
• 1430234-95-9 1-(4-iodophenyl)-5-phenylpenta-1,4-diyn-3-one 
• 1430234-56-2 1-phenyl-5-(1-tosyl-1H-indol-4-yl)penta-1,4-diyn-3-one 
• 1430234-88-0 7,11-dimethyl-1-phenyldodeca-10-en-1,4-diyn-3-one 
• 1430234-92-6 1-((8R,9S,13S,14S,17S)-3,17-dimethoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6Hcyclopenta[a]phenanthren-17-yl)-5-phenylpenta-1,4-diyn-3-one 
• 882866-41-3 3-iodo-2-phenylquinolin-4-(1H)-one 
• 1433174-07-2 6-iodo-8-methoxy-11,11-diphenylisoindolo[2,1-a]quinolin-5(11H)-one 

Relevant articles and documents

CuCl2-catalyzed highly stereoselective and chemoselective reduction of alkynyl amides into α,β-unsaturated amides using silanes as hydrogen donors

A CuH-catalyzed Z-selective partial reduction of alkynyl amides to afford α,β-unsaturated amides using silane as the hydrogen donor is developed. This reaction is carried out under mild conditions and able to accommodate a broad scope of alkynyl amides in

Enantioselective Addition of Alkynyl Ketones to Nitroolefins Assisted by Br?nsted Base/H-Bonding Catalysis

Various sets of enolizable alkynyl ketones (including methyl ynones with α-aryl, α-alkenyl, and α-alkoxy groups) were able to react smoothly with nitroolefins with the assistance of bifunctional Br?nsted base/H-bond catalysts to provide adducts with two consecutive tertiary stereocenters in a highly diastereo- and enantioselective fashion. Further transformation of the obtained adducts into optically active acyclic and polycyclic molecules, including some with intricate carbon skeletons, was also demonstrated.

Controlling the α/γ-Reactivity of Vinylogous Ketone Enolates in Organocatalytic Enantioselective Michael Reactions

The first regio-, diastereo-, and enantioselective direct Michael reaction of β,γ-unsaturated ketones with nitroolefins is enabled by Br?nsted base/hydrogen-bonding bifunctional catalysis. A squaramide-substituted tertiary amine catalyzes the reaction of a broad range of β,γ-unsaturated ketones to proceed at the α-site exclusively, giving rise to adducts with two consecutive tertiary carbon stereocenters in diastereomeric ratios of up to >20:1 and enantioselectivities generally in the 90–98 % ee range.