1330660-72-4Relevant articles and documents
Enantioselective α-arylation of carbonyls via Cu(I)-bisoxazoline catalysis
Harvey, James S.,Simonovich, Scott P.,Jamison, Christopher R.,MacMillan, David W. C.
, p. 13782 - 13785 (2011/10/13)
The enantioselective α-arylation of both lactones and acyl oxazolidones has been accomplished using a combination of diaryliodonium salts and copper catalysis. These mild catalytic conditions provide a new strategy for the enantioselective construction and retention of enolizable α-carbonyl benzylic stereocenters, a valuable synthon for the production of medicinal agents.
