13312-52-2 Usage
Description
(9Z)-β-Carotene is a naturally occurring carotenoid found in various fruits and vegetables, with carrots being one of the highest dietary sources. It is the 9-cis isomer of β-carotene, which differs from the more common (all-E)-β-carotene isomer found in carrots. Although (9Z)-β-carotene has lower bioavailability, provitamin A activity, and antioxidant capacity compared to the (all-E) isomer, it still possesses valuable properties and potential applications.
Uses
Used in Food Industry:
(9Z)-β-Carotene is used as a natural colorant for various food products due to its vibrant orange hue. It imparts a rich color to processed foods, beverages, and supplements, enhancing their visual appeal and providing a healthy alternative to synthetic colorants.
Used in Pharmaceutical Industry:
(9Z)-β-Carotene is used as a provitamin A supplement in the pharmaceutical industry. Although it has lower provitamin A activity compared to the (all-E) isomer, it still contributes to maintaining adequate vitamin A levels in the body, which is essential for maintaining good vision, immune function, and overall health.
Used in Cosmetic Industry:
(9Z)-β-Carotene is used as an ingredient in cosmetic products, such as creams and lotions, due to its antioxidant properties. It helps protect the skin from oxidative stress and environmental damage, promoting a healthy and youthful appearance.
Used in Nutraceutical Industry:
(9Z)-β-Carotene is used as a nutraceutical ingredient in dietary supplements and functional foods. It contributes to the overall health benefits of these products, including immune support, eye health, and antioxidant protection.
Biochem/physiol Actions
(9Z)-β-Carotene or 9-cis-β-carotene is a 9-cis retinoic acid precursor in intestinal mucosal glands of humans. 9-cis retinoic acid is a ligand for nuclear receptor and retinoid X receptor (RXR). 9-cis-β-carotene participates in gene regulation. It is majorly present in liver. 9-cis-β-Carotene supplementation inhibits the progression of atherosclerosis. 9-cis-β-carotene may restore photoreceptors in retinitis pigmentosa (RP) and retinal dystrophies.
Check Digit Verification of cas no
The CAS Registry Mumber 13312-52-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,1 and 2 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 13312-52:
(7*1)+(6*3)+(5*3)+(4*1)+(3*2)+(2*5)+(1*2)=62
62 % 10 = 2
So 13312-52-2 is a valid CAS Registry Number.
13312-52-2Relevant articles and documents
Chlorophyll a Sensitized Trans-Cis Photoisomerization of all-trans-β-Carotene
Jensen, Niels-Henrik,Nielsen, Anne B.,Wilbrandt, Robert
, p. 6117 - 6119 (1982)
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Polgar,Zechmeister
, (1944)
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Zechmeister,Polgar
, p. 137,142, 143 (1944)
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A synthesis method of 9-cis Beta-carotene
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, (2021/05/18)
The present invention relates to a method for synthesizing 9 - cis Beta-carotene (9 - cis beta-carotene) compounds having high purity and easy mass production through a chemical reaction, and a reaction for substituting 9 - cis Retinol groups of Alcohol with 9 - cis Phosphonium salt. The reaction of β - (3 - Methyl-2-butenal to Knoevenagel condensation) to synthesize All-trans Aldehyde. In step 9 - cis Retinoic Phosphonium salt) and in step), the completed All-trans Aldehyde is subjected to Wittig Olefination reaction with carbon double bonds, and 9. cis Beta-carotene obtained by the reaction of carbon double bonds.
METHOD FOR SYNTHESIS OF 9-CIS-BETA-CAROTENE AND FORMULATIONS THEREOF
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, (2017/12/29)
The present invention relates to a method for total chemical synthesis of 9-cis-β-carotene (9CBC), and further provides stable formulations thereof.
