133123-16-7

Basic information

• Product Name: (5R)-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3α,5,17β-triol 3-acetate 5-benzoate 17-propionate
• CAS NO: 133123-16-7
• Molecular Weight: 496.644
• Mol File: 133123-16-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R)-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3α,5,17β-triol 3-acetate 5-benzoate 17-propionate(CAS DataBase Reference)
• NIST Chemistry Reference: (5R)-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3α,5,17β-triol 3-acetate 5-benzoate 17-propionate(133123-16-7)
• EPA Substance Registry System: (5R)-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3α,5,17β-triol 3-acetate 5-benzoate 17-propionate(133123-16-7)

Safety Data

• Hazardous Substances Data: 133123-16-7(Hazardous Substances Data)

Upstream product

• 133127-91-0 (5R)-3,6-cyclo-4-nor-3,5-seco-6β-androstane-3α,5,17β-triol 3-acetate 17-propionate 
• 98-88-4 benzoyl chloride 
• 57-85-2 testosterone propionate 
• 3510-18-7 5-oxo-17β-propionyloxy-4-nor-3,5-secoandrostan-3-oic acid 
• 3510-19-8 17β-propionyloxy-4-oxaandrost-5-en-3-one 
• 133123-12-3 3α-acetoxy-17β-propionyloxy-3,6-cyclo-4-nor-3,5-seco-6β-androstan-5-one 
• 133123-08-7 3α-hydroxy-17β-propionyloxy-3,6-cyclo-4-nor-3,5-seco-6β-androstan-5-one 

Relevant articles and documents

Preparation of Antiandrogenic 17-Hydroxy-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3-one by Deoxygenation of the Corresponding 5-Hydroxy Derivatives

This paper reports on three alternative procedures for the preparation of antiandrogenic 17β-hydroxy-3,6-cyclo-4-nor-3,5-seco-6β-androstan-3-one 15.The key step represents the removal of the oxygen functional group from position 5 which was effected by radical deoxygenation of thioesters of type 13.The variant of choice was the deoxygenation of the 5-thioimidazole 29 prepared from diketone 5.The 3-keto group was selectively protected during hydride reduction by conversion into the corresponding silyl enol ether.