133156-06-6 Usage
Description
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2, also known as GR 73632, is a synthetic peptide and a NK1 tachykinin receptor agonist. It is composed of a sequence of amino acids and has the ability to bind and activate the NK1 receptor, which is involved in various physiological processes.
Used in Pharmaceutical Industry:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 is used as a therapeutic agent for the treatment of asthma and gastrointestinal disorders. Its activation of the NK1 receptor leads to the contraction of muscles, which can help alleviate symptoms associated with these conditions.
Used in Research Applications:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2 is also used as a research tool to study the role of neurokinin receptors and their involvement in various physiological processes. It can help researchers understand the mechanisms of action of neurokinin receptors and develop new therapeutic strategies for related diseases.
Biochem/physiol Actions
GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.
Check Digit Verification of cas no
The CAS Registry Mumber 133156-06-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,1,5 and 6 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 133156-06:
(8*1)+(7*3)+(6*3)+(5*1)+(4*5)+(3*6)+(2*0)+(1*6)=96
96 % 10 = 6
So 133156-06-6 is a valid CAS Registry Number.
InChI:InChI=1/C40H59N7O6S/c1-27(2)24-34(38(51)44-30(36(42)49)20-23-54-4)46(3)40(53)33-18-13-22-47(33)39(52)32(26-29-16-9-6-10-17-29)45-37(50)31(25-28-14-7-5-8-15-28)43-35(48)19-11-12-21-41/h5-10,14-17,27,30-34H,11-13,18-26,41H2,1-4H3,(H2,42,49)(H,43,48)(H,44,51)(H,45,50)/t30-,31-,32-,33-,34-/m0/s1