13316-98-8

Basic information

• Product Name: Benzoic acid, 2-[(2-hydroxybenzoyl)amino]-
• CAS NO: 13316-98-8
• Molecular Formula: C14H11NO4
• Molecular Weight: 257.246
• Mol File: 13316-98-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-[(2-hydroxybenzoyl)amino]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-[(2-hydroxybenzoyl)amino]-(13316-98-8)
• EPA Substance Registry System: Benzoic acid, 2-[(2-hydroxybenzoyl)amino]-(13316-98-8)

Safety Data

• Hazardous Substances Data: 13316-98-8(Hazardous Substances Data)

Usage

General Description

Benzoic acid, 2-[(2-hydroxybenzoyl)amino]- is a chemical compound with the molecular formula C13H11NO4. It is an organic compound that is commonly used in the food and pharmaceutical industries as a preservative and antifungal agent. It is derived from the reaction of benzoic acid with salicylic acid, resulting in a compound with a benzoyl group and an amino group. The presence of the hydroxybenzoyl group in this compound gives it additional antioxidant properties, making it useful in skincare products as well. Benzoic acid, 2-[(2-hydroxybenzoyl)amino]- is a versatile chemical that can be used for a variety of purposes in different industries.

Upstream product

• 107469-44-3 2-(4-oxo-4H-benzo[d][1,2,3]triazin-3-yl)-benzoic acid 
• 1022-46-4 2-phenyl-4H-3,1-benzoxazin-4-one 
• 21958-32-7 2-(2-hydroxyphenyl)-4H-benzo[d][1,3]oxazin-4-one 
• 5538-51-2 O-acetylsalicyloyl chloride 
• 118-92-3 anthranilic acid 
• 69-72-7 salicylic acid 
• 121-44-8 triethylamine 
• 1441-87-8 salicyloyl chloride 
• 117979-60-9 2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)phenyl acetate 

Downstream Products

• 117979-60-9 2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)phenyl acetate 
• 18066-04-1 N-salicyloyl-anthranilic acid ethyl ester 
• 21958-32-7 2-(2-hydroxyphenyl)-4H-benzo[d][1,3]oxazin-4-one 

Relevant articles and documents

Substituent effects on energetics of peptide-carboxylate hydrogen bonds as studied by 1H NMR spectroscopy: Implications for enzyme catalysis

Substituent effects in N-H···O hydrogen bonds were estimated by comparing the acidities of two series of model compounds: N-benzoylanthranilic acids (A) and 4-benzoylamidobenzoic acids (B). Intramolecular N-H···O hydrogen bonds were found to be present in the A series of compounds, while B acids were used as control models. The respective pKa values for A and B acids were determined experimentally in DMSO solution using proton NMR spectroscopy. With X = H, the pKa for A and B acids were observed to be 7.6 and 11.6, respectively, a difference of 4.0 units (ΔpKa). However, with X = p-NO 2, the ΔpKa value between A and B acids increased to 4.7 units: the pKa values for A and B acids were determined as 6.7 and 11.4, respectively. The ΔpKa values between A and B acids as a function of the X substituents were studied in 10 other examples. The effects of X substituents in A acids could be predicted on the basis of the observed linear Hammett correlations, and the sensitivity of each substituent effect was found to be comparable to those observed for the ionization of substituted benzoic acids (ρ = 1.04 for A acids, and ρ = 1.00 for benzoic acids).

Palladium catalyzed chemo- and site-selective C-H acetoxylation and hydroxylation of oxobenzoxazine derivatives

An efficient protocol for the introduction of acetoxy and hydroxy functionalities on unactivated aryl sp2 carbons of oxobenzoxazine derivatives via an ortho-C-H activation reaction using a palladium catalyst has been developed for the first tim

Novel synthesis of dianthalexin (Phytoalexin) analogues preparation

Two phytoalexins, previously isolated from carnation infected by Phytophthora parasitica D., were synthesized: 2-phenyl-7-hydroxy-4H-3,l-benzoxazin-4-one (Dianthalexin) and 2-(2-hydroxybenzoyl)-amino-4-methoxybenzoic acid (Dianthramide A). The first one w