1331771-42-6

Basic information

• Product Name: 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)tetrahydrofuran
• Synonyms: 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)tetrahydrofuran
• CAS NO: 1331771-42-6
• Molecular Weight: 498.77
• Mol File: 1331771-42-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)tetrahydrofuran(CAS DataBase Reference)
• NIST Chemistry Reference: 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)tetrahydrofuran(1331771-42-6)
• EPA Substance Registry System: 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)tetrahydrofuran(1331771-42-6)

Safety Data

• Hazardous Substances Data: 1331771-42-6(Hazardous Substances Data)

Upstream product

• 873-55-2 sodium benzenesulfonate 
• 24163-93-7 farnesyl bromide 
• 1331771-22-2 (E)-3-(5-bromo-4-methylpent-3-enyl)tetrahydrofuran 
• 56881-53-9 (E,E)-farnesyl phenylsulfone 
• 1331771-41-5 (E)-2-methyl-5-(tetrahydrofuran-3-yl)pent-2-en-1-ol 
• 1331771-40-4 (E)-2-methyl-5-(tetrahydrofuran-3-yl)pent-2-enoic acid ethyl ester 
• 1017793-05-3 3-(tetrahydrofuran-3-yl)propanal 
• 1050496-53-1 3-(tetrahydrofuran-3-yl)propan-1-ol 
• 766539-77-9 ethyl 3-(oxolan-3-yl)propanoate 
• 941687-62-3 (E)-3-(tetrahydrofuran-3-yl)acrylic acid ethyl ester 
• 79710-86-4 tetrahydrofuran-3-carboxaldehyde 

Relevant articles and documents

Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge

Structure-activity relationship of furospinosulin-1 (1), a hypoxia-selective growth inhibitor isolated from marine sponge, was investigated. Concise synthetic method of 1 was developed, and some structurally modified analogues were prepared. Biological evaluation of them revealed that the whole chemical structure was important for the hypoxia-selective growth inhibitory activity of 1. Among prepared, the desmethyl analogue 30 showed excellent hypoxia-selective inhibitory activity similar to that of 1 and also exhibited in vivo anti-tumor activity with oral administration.