1332323-45-1Relevant articles and documents
Activity of steroid 4 and derivatives 4a–4f as inhibitors of the enzyme 5α-reductase 1
Arellano, Yazmín,Bratoeff, Eugene,Heuze, Yvonne,Bravo, Marisol,Soriano, Juan,Cabeza, Marisa
, p. 4058 - 4064 (2018/07/21)
It is known that the growth of prostate metastatic bone tumor depends on androgens, and tumor formation can start from migratory malignant cells produced in that organ. These cells exhibit grater type 1 5α-reductase (5α-R1) activity than type 2 5α-reducta
In vivo and in vitro effect of androstene derivatives as 5α-reductase type 1 enzyme inhibitors
Bratoeff, Eugene,Sanchez, Araceli,Arellano, Yazmin,Heuze, Yvonne,Soriano, Juan,Cabeza, Marisa
, p. 1247 - 1254 (2013/12/04)
The aim of these studies was to synthesize twelve ester derivatives of dehydroepiandrosterone with therapeutic potential. The effect of 1-12 was demonstrated in the flank organs of gonadectomized hamsters treated with testosterone and the synthesized ster
