13324-82-8

Basic information

• Product Name: 4(1H)-Quinazolinone, 2,3-dihydro-2-[(1E)-2-phenylethenyl]-
• CAS NO: 13324-82-8
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 13324-82-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 2,3-dihydro-2-[(1E)-2-phenylethenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 2,3-dihydro-2-[(1E)-2-phenylethenyl]-(13324-82-8)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 2,3-dihydro-2-[(1E)-2-phenylethenyl]-(13324-82-8)

Safety Data

• Hazardous Substances Data: 13324-82-8(Hazardous Substances Data)

Upstream product

• 101350-27-0 2-[(E)-3-phenylpropen-2-ylideneamino]benzamide 
• 28144-70-9 anthranilic acid amide 
• 14371-10-9 (E)-3-phenylpropenal 
• 610-15-1 2-nitrobenzamide 
• 118-48-9 isatoic anhydride 

Relevant articles and documents

One-pot B(C6F5)3 catalyzed cascade synthesis of 2-substituted-2,3-dihydroquinazolin-4(1H)-ones

A new and efficient B(C6F5)3 catalyzed domino strategy has been developed for the synthesis of 2-substituted quinazolinones. The reaction utilizes 2-aminobenzamide and aldehydes for a one-pot protocol. A wide range of substrate scope, functional group tolerance, and operational simplicity with excellent yield are synthetically useful features.

KOH/DMSO: A basic suspension for transition metal-free Tandem synthesis of 2,3-dihydroquinazolin-4(1H)-ones

A novel protocol for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones from 2-aminobenzamides and aldehyde derivatives catalyzed by KOH/DMSO suspension has been developed. The present transition metal free methodology is operationally simple, scalable and varieties of 2,3-dihydroquinazolin-4(1H)-one derivatives were obtained in good to excellent yields in short reaction times.

A concise aqueous phase supramolecular synthesis of 2-phenyl-2,3- dihydroquinazolin-4(1H)-one derivatives

2-Phenyl-2,3-dihydroquinazolin-4(1H)-one derivatives were synthesized for the first time in water under neutral conditions by the reaction of aldehyde, and anthranilamide mediated by β-cyclodextrin in high yields. β-Cyclodextrin can be recovered and reused with a small loss of catalytic activity.