1332703-43-1

Basic information

• Product Name: 6-bromo-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo-[1,2-a]pyridine
• Synonyms: 6-bromo-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo-[1,2-a]pyridine
• CAS NO: 1332703-43-1
• Molecular Weight: 341.207
• Mol File: 1332703-43-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-bromo-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo-[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-bromo-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo-[1,2-a]pyridine(1332703-43-1)
• EPA Substance Registry System: 6-bromo-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo-[1,2-a]pyridine(1332703-43-1)

Safety Data

• Hazardous Substances Data: 1332703-43-1(Hazardous Substances Data)

Upstream product

• 4044-98-8 6-bromo-2-phenylimidazo[1,2-a]pyridine 
• 1332703-42-0 6-bromo-3-iodo-2-phenylimidazo[1,2-a]pyridine 
• 627-41-8 propargyl alcohol methyl ether 
• 1072-97-5 5-bromo-2-pyridylamine 

Downstream Products

• 1332703-58-8 6-(4-methoxyphenyl)-3-(3-methoxyprop-1-ynyl)-2-phenylimidazo[1,2-a]pyridine 
• 1332703-60-2 3-(3-methoxyprop-1-ynyl)-2-phenyl-6-phenylethynylimidazo[1,2-a]pyridine 

Relevant articles and documents

Pd-catalyzed regiocontrolled Sonogashira and Suzuki cross-coupling reaction of 3,6-dihalogenoimidazo[1,2-a]pyridines: One-pot double-coupling approach

New and efficient regioselective Sonogashira and Suzuki-Miyaura palladium-catalyzed coupling reactions of 3,6-dihalogenoimidazo[1,2-a]pyridines followed by another cross-coupling has been successfully developed. Various solvents, palladium species and bases were tested. Scope and limitations of this regiocontrolled palladium-catalyzed reaction were investigated. The synthesis of 3,6-disubstituted imidazo[1,2-a]pyridine derivatives using one-pot regioselective double-coupling approach was developed. This procedure affords convergent syntheses of polysubstituted compounds in high yields in a very few steps.