1332862-61-9Relevant articles and documents
Chemoenzymatic dynamic kinetic resolution as a key step in the enantioselective synthesis of (S)-salbutamol
Traeff, Annika,Solarte, Carmen E.,Baeckvall, Jan-E.
, p. 919 - 927 (2012/02/01)
The synthesis of (S)-salbutamol is described. By utilizing DKR in the enantiodetermining step, employing Burkholderia cepacia lipase (PS-IM), (S)-acetate ((S)-6) was obtained in excellent enantiomeric excess (98%). The subsequent transformations yielded t