1333128-00-9

Basic information

• Product Name: 3-[4-[(E)-styryl]phenyl]imidazo[1,2-a]pyridine
• Synonyms: 3-[4-[(E)-styryl]phenyl]imidazo[1,2-a]pyridine
• CAS NO: 1333128-00-9
• Molecular Weight: 296.371
• Mol File: 1333128-00-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-[4-[(E)-styryl]phenyl]imidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-[4-[(E)-styryl]phenyl]imidazo[1,2-a]pyridine(1333128-00-9)
• EPA Substance Registry System: 3-[4-[(E)-styryl]phenyl]imidazo[1,2-a]pyridine(1333128-00-9)

Safety Data

• Hazardous Substances Data: 1333128-00-9(Hazardous Substances Data)

Upstream product

• 106-39-8 bromochlorobenzene 
• 274-76-0 imidazo[1,2-a]pyridine 
• 1657-50-7 (E)-1-(4-chlorophenyl)-2-phenylethene 
• 100-42-5 styrene 
• 663946-08-5 3-(4-chlorophenyl)-imidazo[1,2-a]pyridine 

Relevant articles and documents

Direct C5-arylation reaction between imidazoles and aryl chlorides catalyzed by palladium complexes with phosphines and N-heterocyclic carbenes

Palladium(II) acetate complexes bearing phosphines and carbene ligands, Pd(L)(PR3)(OAc)2 (1a, R = Ph; 1b, R = Cy; L = 1,3-dibenzylimidazol-2-ylidene), were prepared by salt metathesis reactions of their chloro complexes with AgOAc in good yields. The electron-rich 1b was efficient in catalyzing C-5 direct arylation of imidazoles with aryl halides. Most significantly, the catalytic system allows a range of aryl chlorides as substrates. Microwave irradiation effectively promotes the reactions, with good yields obtainable in only 2 h. In combination with the classical method of C-C bond formation reactions, novel imidazole derivatives featuring biaryl and styryl subunits were successfully obtained from 1,4-dichlorobenzene and 1-bromo-4-chlorobenzene.