1333419-38-7

Basic information

• Product Name: (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate
• Synonyms: (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate
• CAS NO: 1333419-38-7
• Molecular Weight: 259.305
• Mol File: 1333419-38-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate(1333419-38-7)
• EPA Substance Registry System: (Z)-methyl 3-(2-oxopyrrolidin-1-yl)-3-(m-tolyl)acrylate(1333419-38-7)

Safety Data

• Hazardous Substances Data: 1333419-38-7(Hazardous Substances Data)

Upstream product

• 625-95-6 3-Iodotoluene 
• 145294-78-6 1-[(E)-2-(methoxycarbonyl)vinyl]-2-pyrrolidinone 
• 253342-48-2 4,4,5,5-tetramethyl-2-m-tolyl-1,3,2-dioxaborolane 

Relevant articles and documents

Arylations of substituted enamides by aryl iodides: Regio- and stereoselective synthesis of (z)-β-amido-β-arylacrylates

Arylations of substituted enamides by aryl iodides were achieved for the first time via an unusual PdCl2(COD)/Ag3PO4 catalytic system. A broad range of (Z)-β-amido-β-arylacrylates were prepared regio- and stereoselectively in a highly efficient manner.

Stereoselective synthesis of highly substituted enamides by an oxidative heck reaction

Functionalization of enamides under Heck conditions has been limited to those with unsubstituted vinyl groups. By tuning reaction parameters that allow for the balance between stability and reactivity of reactants, the oxidative Heck cross-coupling to produce highly substituted enamides in good to excellent yields was achieved (see scheme). Copyright