1333491-55-6

Basic information

• Product Name: C₁₈H₂₂N₄O
• CAS NO: 1333491-55-6
• Molecular Weight: 310.399
• Mol File: 1333491-55-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₂N₄O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₂N₄O(1333491-55-6)
• EPA Substance Registry System: C₁₈H₂₂N₄O(1333491-55-6)

Safety Data

• Hazardous Substances Data: 1333491-55-6(Hazardous Substances Data)

Upstream product

• 941972-59-4 C₁₁H₉BrN₂O 
• 93643-24-4 (S)-octahydropyrrolo[1,2-a]pyrazine 
• 52239-77-7 2-methyl-6-(4-bromophenyl)-4,5-dihydro-3(2H)-pyridazinone 
• 6340-79-0 4-oxo-4-(4-bromophenyl)butanoic acid 

Relevant articles and documents

Amine-constrained pyridazinone histamine H3 receptor antagonists

Pyridazinone 1 was recently reported as a potent H3R antagonist with good drug-like properties and in vivo activity. A series of constrained amine analogs of 1 was synthesized to identify compounds with improved pharmacokinetic profiles. From these efforts, a new class of (S)-2-pyrrolidin-1-ylmethyl-1-pyrrolidinyl amides was identified.