13336-72-6

Basic information

• Product Name: N,N'-Bis-<α-(O,O-dimethyl-phosphono)-benzyl>-p-phenylendiamin
• Synonyms: N,N'-Bis-<α-(O,O-dimethyl-phosphono)-benzyl>-p-phenylendiamin
• CAS NO: 13336-72-6
• Molecular Weight: 504.46
• Mol File: 13336-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N,N'-Bis-<α-(O,O-dimethyl-phosphono)-benzyl>-p-phenylendiamin(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-Bis-<α-(O,O-dimethyl-phosphono)-benzyl>-p-phenylendiamin(13336-72-6)
• EPA Substance Registry System: N,N'-Bis-<α-(O,O-dimethyl-phosphono)-benzyl>-p-phenylendiamin(13336-72-6)

Safety Data

• Hazardous Substances Data: 13336-72-6(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 868-85-9 Dimethyl phosphite 
• 106-50-3 1,4-phenylenediamine 
• 96-36-6 methyl phosphite 
• 797-20-6 N,N'-dibenzylidene-benzene-1,4-diamine 

Relevant articles and documents

Highly efficient one-pot multi-component synthesis of α- aminophosphonates and bis-α-aminophosphonates catalyzed by heterogeneous reusable silica supported dodecatungstophosphoric acid (DTP/SiO2) at ambient temperature and their antitubercular evaluation against Mycobactrium Tuberculosis

A highly efficient one-pot multi-component reaction (MCR) protocol over DTP/SiO2 has been developed for the synthesis of α- aminophosphonate derivatives (4a-x) in excellent yields. The α-aminophosphonate derivatives were for the first time evaluated for their antitubercular activity against the M. tuberculosis H37Ra (MTB) strain. An evaluation of the data on the cytotoxicity and antimicrobial activity shows that 4n and 4v are promising antitubercular agents.