133437-43-1Relevant articles and documents
Copper-catalysed selective 3-sulfonylation of indoles: A mild synthesis of indolyl sulfones
Du, Yi,Liu, Yunyun
, p. 579 - 582 (2016)
The selective C3-sulfonylation of some 4-, 5- and 6-substituted indoles using sodium arenesulfinates as reaction partners has been realised under mild conditions using catalytic CuI/1,10-phenanthroline at 70 °C. The reaction had a satisfactory application
Palladium-Catalyzed Direct C2-Biarylation of Indoles
Murugesan, Tamilarasu,Sivarajan, Chinraj,Jayakumari, Chithra Mohan,Singh, Rajat Kumar,Vennapusa, Sivaranjana Reddy,Kaliyamoorthy, Alagiri
, p. 10838 - 10851 (2021/08/16)
Biaryl and indole units are important structural motifs in several bioactive molecules and functional materials. We have accomplished straightforward access to C2-biarylated indole derivatives through palladium-catalyzed C-H activation strategy with a bro
Catalyst-controlled selectivity in C-S bond formation: Highly efficient synthesis of C2- and C3-sulfonylindoles
Yang, Yong,Li, Wanmei,Xia, Chengcai,Ying, Beibei,Shen, Chao,Zhang, Pengfei
, p. 304 - 307 (2016/02/05)
Exploring a potential catalyst system for catalyst-controlled selectivity in C-S bond formation is a fascinating challenge. Herein, we described two novel and highly efficient methods for the selective synthesis of C2- and C3-sulfonylindoles showing good biological activities by employing iodide and copper catalysts, respectively. Mechanistic studies point to the crucial role of the electronic properties of the sulfonylated intermediates. I see two and I see three: Two novel and highly efficient methods for the selective synthesis of C2- and C3-sulfonylindoles by employing iodide and copper catalysts, respectively, are described. Mechanistic studies point to the crucial role of the electronic properties of the sulfonylated intermediates. phen=1,10-phenantroline, TBHP=tert-butyl hydroperoxide.
