133438-58-1 Usage
Description
Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]is a complex organic compound with a unique molecular structure. It is characterized by its naphthalene and indole moieties, which are connected through a methanone group. Methanone,
(4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]is of interest in various fields due to its potential applications and properties.
Uses
1. Used in Pharmaceutical Industry:
Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]is used as a pharmaceutical compound for its potential therapeutic applications. Its unique structure allows it to interact with specific biological targets, making it a promising candidate for the development of new drugs.
2. Used in Research and Development:
Methanone,
(4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]is also used in research and development settings, where it can be studied for its chemical properties, interactions with biological systems, and potential applications in various fields, including medicine, materials science, and chemical engineering.
3. Used in Forensic Applications:
Due to its unique structure and properties, Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]may also be used in forensic applications, such as the identification and analysis of trace amounts of substances in criminal investigations.
4. Used in Chemical Synthesis:
As a complex organic molecule, Methanone, (4-methyl-1-naphthalenyl)[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]can be used as a starting material or intermediate in the synthesis of other compounds, potentially leading to the development of new materials and products with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 133438-58-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,4,3 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 133438-58:
(8*1)+(7*3)+(6*3)+(5*4)+(4*3)+(3*8)+(2*5)+(1*8)=121
121 % 10 = 1
So 133438-58-1 is a valid CAS Registry Number.
133438-58-1Relevant articles and documents
3-Indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor
Huffman, John W.,Mabon, Ross,Wu, Ming-Jung,Lu, Jianzhong,Hart, Richard,Hurst, Dow P.,Reggio, Patricia H.,Wiley, Jenny L.,Martin, Billy R.
, p. 539 - 549 (2007/10/03)
A series of 1-pentyl-1H-indol-3-yl-(1-naphthyl)methanes (9-11) and 2-methyl-1-pentyl-1H-indol-3-yl-(1-naphthyl)methanes (12-14) have been synthesized to investigate the hypothesis that cannabimimetic 3-(1-naphthoyl)indoles interact with the CB1 receptor by hydrogen bonding to the carbonyl group. Indoles 9-11 have significant (Ki=17-23 nM) receptor affinity, somewhat less than that of the corresponding naphthoylindoles (5, 15, 16). 2-Methyl-1-indoles 12-14 have little affinity for the CB1 receptor, in contrast to 2-methyl-3-(1-naphthoyl)indoles 17-19, which have affinities comparable to those of 5, 15, 16. A cannabimimetic indene hydrocarbon (26) was synthesized and found to have Ki=26±4 nM. Molecular modeling and receptor docking studies of naphthoylindole 16, its 2-methyl congener (19) and indolyl-1-naphthylmethanes 11 and 14, combined with the receptor affinities of these cannabimimetic indoles, strongly suggest that these cannabinoid receptor ligands bind primarily by aromatic stacking interactions in the transmembrane helix 3-4-5-6 region of the CB1 receptor.
