1334396-07-4Relevant articles and documents
Total synthesis of paecilospirone
Yuen, Tsz-Ying,Yang, Sung-Hyun,Brimble, Margaret A.
, p. 8350 - 8353 (2011/10/31)
Neutrality is the best policy: Key features of the first total synthesis of paecilospirone include an anti-selective, lactate-derived aldol reaction, and a double deallylation/spirocyclization conducted at neutral pH to construct the sensitive hydroxy-substituted benzannulated spiroacetal (see scheme; Bn=benzyl, TBS=tert-butyldimethylsilyl, TES=triethylsilyl).