133448-22-3

Basic information

• Product Name: BOC-GLU(OBZL)-GLY-ARG-AMC HCL
• Synonyms: BOC-GLU(OBZL)-GLY-ARG-7-AMIDO-4-METHYLCOUMARIN HCL;BOC-GLU(OBZL)-GLY-ARG-AMC HCL;N-T-BOC-GAMMA-BENZYL-GLU-GLY-ARG 7-AMIDO-4-METHYLCOUMARIN HYDROCHLORIDE;N-T-boc-gamma-benzyl-glu-gly-arg 7-*amido-4-methy;N-T-BOC-GAMMA-BENZYL-GLU-GLY-ARG 7-AMIDO -4-METHYLC;boc-γ-benzyl-glu-gly-arg-7-amido-4-methylcoumarin hydrochloride;BOC-GLU(OBZL)-GLY-ARG-MCA[HYDROCHLORIDE FORM];N-BOC-gamma-benzyl-Glu-Gly-Arg-7-amido-4-methylcoumarinHCl
• CAS NO: 133448-22-3
• Molecular Formula: C35H46ClN7O9
• Molecular Weight: 744.23
• Product Categories: Activity;Enzyme Substrates;Fluorogenic
• Mol File: 133448-22-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 1038.5°C at 760 mmHg
• Flash Point: 581.9°C
• Appearance: /
• Vapor Pressure: 0mmHg at 25°C
• Storage Temp.: −20°C
• CAS DataBase Reference: BOC-GLU(OBZL)-GLY-ARG-AMC HCL(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-GLU(OBZL)-GLY-ARG-AMC HCL(133448-22-3)
• EPA Substance Registry System: BOC-GLU(OBZL)-GLY-ARG-AMC HCL(133448-22-3)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 133448-22-3(Hazardous Substances Data)

Usage

Description

BOC-GLU(OBZL)-GLY-ARG-AMC HCL is a synthetic peptide compound that serves as a substrate for various enzymes, including coagulation factors IXa and XIIa, as well as trypsin and soybean trypsin-like enzyme. It is characterized by its yellowish powder appearance and plays a significant role in the study and analysis of enzyme activity and function.

Uses

1. Used in Pharmaceutical Industry:
BOC-GLU(OBZL)-GLY-ARG-AMC HCL is used as a substrate for the assessment of enzyme activity in the development of drugs targeting coagulation factors and trypsin-like enzymes. Its application aids in understanding the interactions between these enzymes and potential therapeutic agents, ultimately contributing to the advancement of treatments for related conditions.
2. Used in Research and Development:
In the field of research, BOC-GLU(OBZL)-GLY-ARG-AMC HCL is utilized as a reagent for studying the mechanisms of action and specificity of coagulation factors IXa, XIIa, trypsin, and soybean trypsin-like enzyme. This knowledge is crucial for the development of targeted therapies and the improvement of existing treatments.
3. Used in Diagnostic Applications:
BOC-GLU(OBZL)-GLY-ARG-AMC HCL serves as a diagnostic tool in the detection and monitoring of enzyme levels and activities in various diseases and conditions. Its use in diagnostic assays helps in the early identification of abnormalities and the assessment of treatment efficacy.
4. Used in Quality Control:
In the biotechnology and pharmaceutical industries, BOC-GLU(OBZL)-GLY-ARG-AMC HCL is employed as a quality control standard for the validation of enzyme assays and the assessment of enzyme purity and activity. This ensures the reliability and accuracy of enzyme measurements in research and drug development processes.

InChI:InChI=1/C35H45N7O9.ClH/c1-21-17-30(45)50-27-18-23(12-13-24(21)27)40-32(47)25(11-8-16-38-33(36)37)41-28(43)19-39-31(46)26(42-34(48)51-35(2,3)4)14-15-29(44)49-20-22-9-6-5-7-10-22;/h5-7,9-10,12-13,17-18,25-26H,8,11,14-16,19-20H2,1-4H3,(H,39,46)(H,40,47)(H,41,43)(H,42,48)(H4,36,37,38);1H