133463-51-1Relevant articles and documents
Alpha Synuclein Fibrils Contain Multiple Binding Sites for Small Molecules
Hsieh, Chia-Ju,Ferrie, John J.,Xu, Kuiying,Lee, Iljung,Graham, Thomas J. A.,Tu, Zhude,Yu, Jennifer,Dhavale, Dhruva,Kotzbauer, Paul,Petersson, E. James,Mach, Robert H.
, p. 1 - 13 (2018)
The fibrillary aggregation of the protein alpha synuclein (Asyn) is a hallmark of Parkinson's disease, and the identification of small molecule binding sites on fibrils is essential to the development of diagnostic imaging probes. A series of molecular mo
Stereoselective synthesis of phenyl-1,2,3-triazoles containing (E)-vinyl halide group via a one-pot, three-component reaction
Zhang, Wensheng,Su, Changhui,Kuang, Chunxiang,Yang, Qing
, p. 1267 - 1275 (2011/05/11)
Phenyl-1,2,3-triazoles containing (E)-vinyl halide were readily synthesized via a one-pot, three-component reaction of 3-(4- or 2-azidophenyl)acrylic acid, NXS(X=Cl, Br and I) and 1-alkynes in MeCN-H2O (9:1v/v) catalyzed by LiOAc/CuI-sodium ascorbate syst
Synthesis of novel and photolabile philanthotoxin analogs: Glutamate receptor antagonists
Choi,Goodnow,Kalivretenos,Chiles,Fushiya,Nakanishi
, p. 4793 - 4822 (2007/10/02)
The synthetic methods for 27 novel and photolabile philanthotoxin analogs are described. Most analogs were synthesized by two general methods with modifications of these methods where necessary.