133562-34-2

Basic information

• Product Name: 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE
• Synonyms: 2-AMINO-1-O-TOLYL-ETHANOL HYDROCHLORIDE;2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE;Benzenemethanol, -alpha--(aminomethyl)-2-methyl- (9CI);BENZENEMETHANOL, α-(AMINOMETHYL)-2-METHYL-;2-Amino-1-(2-methylphenyl)ethanol HCl;2-Amino-1-(2-iodophenyl)ethanol
• CAS NO: 133562-34-2
• Molecular Formula: C9H13NO
• Molecular Weight: 151.20562
• Product Categories: PHENYL
• Mol File: 133562-34-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE(133562-34-2)
• EPA Substance Registry System: 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE(133562-34-2)

Safety Data

• Hazardous Substances Data: 133562-34-2(Hazardous Substances Data)

Usage

General Description

2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE is a chemical compound with the molecular formula C8H10INOHCl. It is a synthetic organic compound that contains an amino group and a hydroxyl group attached to a benzene ring with an iodine substituent. 2-AMINO-1-(2-IODO-PHENYL)-ETHANOL HYDROCHLORIDE is commonly used in the pharmaceutical industry for the synthesis of various drugs and as a reagent in organic chemistry. Its hydrochloride salt form makes it more stable and easier to handle in laboratory settings. It is also used as a building block in the synthesis of other organic compounds.

Upstream product

• 114579-90-7 (R)-2-(2-methylphenyl)-2-trimethylsilyloxyacetonitrile 
• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 2783-26-8 o-methylstyrene oxide 
• 868151-97-7 (S)-2-nitro-1-o-tolyl-ethanol 
• 141303-27-7 2-chloro-1-(o-tolyl)ethan-1-ol 
• 611-15-4 1-methyl-2-vinyl-benzene 
• 529-20-4 2-methylphenyl aldehyde 

Relevant articles and documents

Regio-selective synthesis of 1,2-aminoalcohols from epoxides and chlorohydrins

A simple and efficient procedure for the regio-selective synthesis of 1,2-aminoalcohols from terminal epoxides and chlorohydrins by using NaHMDS as the source of amine is reported. The wider scope and utility of this method is demonstrated.

Chiral-Organotin-Catalyzed Kinetic Resolution of Vicinal Amino Alcohols

A highly efficient kinetic resolution of racemic amino alcohols has been achieved for the first time with a chiral tin catalyst. A chiral organotin compound with 3,4,5-trifluorophenyl groups at the 3,3′-positions of the binaphthyl framework enabled this transformation with excellent yield and high enantioselectivity. The process tolerates aryl- and alkyl-substituted amino alcohols and a variety of other substrates, affording the corresponding products in high enantioselectivity and with s factors up to >500.

Direct catalytic synthesis of unprotected 2-amino-1-phenylethanols from alkenes by using iron(II) phthalocyanine

Aryl-substituted amino alcohols are privileged scaffolds in medicinal chemistry and natural products. Herein, we report that an exceptionally simple and inexpensive FeII complex efficiently catalyzes the direct transformation of simple alkenes into unprotected amino alcohols in good yield and perfect regioselectivity. This new catalytic method was applied in the expedient synthesis of bioactive molecules and could be extended to aminoetherification.