133565-48-7

Basic information

• Product Name: N^ω-Hydroxy-L-arginine dihydrochloride
• CAS NO: 133565-48-7
• Molecular Weight: 263.124
• Mol File: 133565-48-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N^ω-Hydroxy-L-arginine dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N^ω-Hydroxy-L-arginine dihydrochloride(133565-48-7)
• EPA Substance Registry System: N^ω-Hydroxy-L-arginine dihydrochloride(133565-48-7)

Safety Data

• Hazardous Substances Data: 133565-48-7(Hazardous Substances Data)

Upstream product

• 45234-13-7 N²-(tert-butoxycarbonyl)-N⁵-carbamoyl-L-ornithine 
• 149970-88-7 tert-butyl N^α-Boc-N^G-(benzyloxy)-L-arginate 
• 133565-52-3 α-N-t-butoxycarbonyl-N^G-benzyloxy-N^6'-t-butoxycarbonyl-L-arginine-t-butyl ester 
• 133565-51-2 α-N-(tert-butoxycarbonyl)-δ-<(N¹-(tert-butoxycarbonyl)-S-methyl)-1-isothioureido>-L-norvaline tert-butyl ester 
• 133565-50-1 (S)-2-tert-Butoxycarbonylamino-5-(2-methyl-isothioureido)-pentanoic acid tert-butyl ester 
• 133565-49-8 α-N-t-butoxycarbonyl-δ-(thioureido)-L-norvaline-t-butyl ester 
• 225530-13-2 α-N-tert-butoxycarbonyl-δ-N-isothiocyanato-L-ornithine tert-butyl ester 
• 149970-80-9 tert-butyl N^α-Boc-L-citrullinate 
• 372-75-8 Citrulline 
• 53054-02-7 N_α-(1,1-dimethylethoxycarbonyl)-N_δ-(phenylmethoxycarbonyl)-L-ornithine 1,1-dimethylethyl ester 
• 53054-01-6 (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid tert-butyl ester 
• 53054-03-8 tert-butyl (2S)-5-amino-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanoate 
• 133374-42-2 N^α-(tert-butoxycarbonyl)-N^δ-cyano-L-ornithine tert-butyl ester 
• 133374-43-3 N^α-tert-butyloxycarbonyl-N^ω-hydroxy-L-arginine tert-butyl ester 

Relevant articles and documents

Synthesis of 15N omega-hydroxy-L-arginine and ESR and 15N-NMR studies for the elucidation of the molecular mechanism of enzymic nitric oxide formation from L-arginine.

N omega-Hydroxy-L-arginine (2) was prepared by a multi-stage synthesis; the key step was the addition of hydroxylamine to the protected cyanamide 8. The presence of N-hydroxyguanidines was confirmed, above all, by 15N-NMR investigations. 15N omega-Hydroxy

Methodology for the Preparation of N-Guanidino-Modified Arginines and Related Derivatives

Methods for the preparation of NG-modified arginines and Nδ-heterocyclic ornithines are described.The reactive cyanamide intermediate tert-butyl Nα-Boc-Nδ-cyano-L-ornithinate (2), prepared either by treatment of