133605-27-3

Basic information

• Product Name: 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL
• Synonyms: 2-Nitro-4-(trifluoroMethyl)benzyl alcohol, 97+%;[2-Nitro-4-(trifluoromethyl)phenyl]methanol, 4-(Hydroxymethyl)-3-nitrobenzotrifluoride;2-NITRO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL;(2-Nitro-4-(trifluoromethyl)phenyl)methanol
• CAS NO: 133605-27-3
• Molecular Formula: C₈H₆F₃NO₃
• Molecular Weight: 221.13
• Product Categories: Benzhydrols, Benzyl & Special Alcohols
• Mol File: 133605-27-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 63-65℃
• Appearance: /
• Refractive Index: 1.507
• CAS DataBase Reference: 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(133605-27-3)
• EPA Substance Registry System: 2-NITRO-4-(TRIFLUOROMETHYL)BENZYL ALCOHOL(133605-27-3)

Safety Data

• Hazardous Substances Data: 133605-27-3(Hazardous Substances Data)

Usage

Uses

Used as important intermediates and reagents in organic synthesis. Also used as solvents.

InChI:InChI=1/C8H6F3NO3/c9-8(10,11)6-2-1-5(4-13)7(3-6)12(14)15/h1-3,13H,4H2

Upstream product

• 320-94-5 2-nitro-4-trifluoromethylbenzoic acid 
• 890434-87-4 2-nitro-4-trifluoromethylbenzyl acetate 
• 225656-59-7 1-(chloromethyl)-2-nitro-4-(trifluoromethyl)benzene 

Downstream Products

• 186602-93-7 [2-amino-4-(trifluoromethyl)phenyl]methan-1-ol 
• 890434-86-3 1-methoxymethyl-2-nitro-4-trifluoromethylbenzene 
• 890434-85-2 2-methoxymethyl-5-trifluoromethylphenylamine 
• 162333-02-0 1-(bromomethyl)-4-(trifluoromethyl)-2-nitrobenzene 

Relevant articles and documents

Intramolecular Pd-catalyzed reductive amination of enolizable sp3-C-H bonds

A palladium-catalyzed reductive cyclization of nitroarenes has been designed to construct sp3-C-NHAr bonds from sp3-C-H bonds by using an enolizable nucleophile to intercept a nitrosoarene intermediate. Exposure of ortho-substituted nitroarenes to 5 mol ?% of Pd(OAc)2 and 10 mol ?% of phenanthroline under 2 atm of CO constructs partially saturated 5-, 6-, or 7-membered N-heterocycles using α-pyridyl carboxylates, malonates, 1,3-dimethylbarbituric acid, 1,3-diones, or difurans as the nucleophile.

Substituted Indoles, Compositions Containing Them, Method for the Production Thereof and Their Use

Compounds of formula (I): wherein R1, R5, R6, R7, Ar, L, A, and Q are as defined in the description, and to salts thereof, to compositions containing them, to the process for preparing them, and to their use as medicinal products, in particular as antican

Resist materials

A class of resist compositions sensitive to deep ultraviolet radiation includes a resin sensitive to acid and a composition that generates acid upon exposure to such radiation. A group of nitrobenzyl materials is particularly suitable for use as the acid generator.