133627-17-5

Basic information

• Product Name: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one
• Synonyms: Nevirapine Related CoMpound A;Nevirapine Related Compound A (15 mg) (5,11-dihydro-6H-11-ethyl-4-methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one);BIRH 414;11-Ethyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one;BIRH 414 BS;Nevirapine impurity Ⅱ{11-ethyl-4-methyl-5,11-dihydro-6H-dipyrido[3,2-b:2′,3′-e][1,4] diazepin-6-one};5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one;11-ethyl-4-methyl-5H-dipyrido[2,3-e:2',3'-f][1,4]diazepin-6-one
• CAS NO: 133627-17-5
• Molecular Formula: C14H14N4O
• Molecular Weight: 254
• Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 133627-17-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 212-214℃ (1,2-dichloroethane )
• Boiling Point: 389.8°Cat760mmHg
• Flash Point: 189.5°C
• Appearance: /
• Density: 1.224g/cm³
• PKA: 12.05±0.20(Predicted)
• CAS DataBase Reference: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one(133627-17-5)
• EPA Substance Registry System: 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one(133627-17-5)

Safety Data

• Hazardous Substances Data: 133627-17-5(Hazardous Substances Data)

Usage

Description

5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one is a complex organic compound with a unique chemical structure. It belongs to the class of diazepinones and is characterized by its specific arrangement of atoms and functional groups. This molecule has potential applications in various fields due to its chemical properties and interactions with other molecules.

Uses

Used in Pharmaceutical Industry:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one is used as a pharmaceutical compound for its potential therapeutic effects. It may be employed in the development of new drugs targeting specific diseases or conditions, due to its ability to interact with biological targets and modulate cellular processes.
Used in Chemical Research:
In the field of chemical research, 5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one serves as a valuable compound for studying its chemical properties, reactivity, and potential applications in various chemical reactions. Researchers can use this molecule to explore new synthetic pathways, develop novel chemical methods, and gain insights into its structure-activity relationships.
Used as an Impurity in Nevirapine Production:
5,11-dihydro-6H-11-ethyl-4-Methyl-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one is an impurity found in the production of Nevirapine (N391275), an antiretroviral medication used to treat HIV-1 infection. The presence of this compound in the manufacturing process may affect the quality, efficacy, or safety of the final product. Therefore, it is essential to monitor and control the levels of this impurity during the production of Nevirapine to ensure the desired pharmaceutical quality.

Upstream product

• 135795-45-8 N-(2-chloro-4-methyl-3-pyridinyl)-2-ethylamino-3-pyridinecarboxamide 
• 49609-84-9 2-Chloronicotinoyl chloride 
• 23056-39-5 2-chloro-3-nitro-4-methylpyridine 
• 133627-45-9 3-Amino-2-chloro-4-methylpyridine 
• 133627-46-0 2-chloro-N-(2-chloro-4-methyl-3-pyridinyl)-3-pyridinecarboxamide 

Relevant articles and documents

5,11-dihydro-6H-dipyrido(3,2-B:2',3'-E)(1,4)diazepines and their use in the prevention or treatment of HIV infection

Disclosed are novel 5,11-dihydro-6H-dipyrido[3,2-b; 2',3'-e][1,4]diazepines. These are useful in the prevention or treatment of HIV infection.