133662-20-1 Usage
Description
1-(2-chlorophenyl)-2-hydroxyethanone, also known as chlorophenyl ketone, is an organic compound characterized by the chemical formula C8H7ClO2. It presents as a pale yellow solid and possesses a sweet, floral scent. 1-(2-chlorophenyl)-2-hydroxyethanone is recognized for its applications in various industries, particularly as a flavoring and fragrance agent, and also serves as a crucial intermediate in the production of pharmaceuticals and the synthesis of other organic compounds.
Uses
Used in Flavoring and Fragrance Industry:
1-(2-chlorophenyl)-2-hydroxyethanone is utilized as a flavoring and fragrance agent due to its distinctive sweet, floral odor. It enhances the sensory experience of various consumer products, contributing to their appeal and marketability.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(2-chlorophenyl)-2-hydroxyethanone is employed as an intermediate. Its chemical properties make it a valuable component in the synthesis of a range of medicinal compounds, aiding in the development of new drugs and therapies.
Used in Organic Synthesis:
1-(2-chlorophenyl)-2-hydroxyethanone also plays a significant role in organic synthesis, where it is used as a building block for creating other complex organic compounds. Its versatility in chemical reactions allows for the production of a variety of specialty chemicals used across different sectors.
Safety Considerations:
It is imperative to handle 1-(2-chlorophenyl)-2-hydroxyethanone with care, as it can cause irritation to the skin, eyes, and respiratory system if not properly managed. Adherence to safety protocols is essential to prevent any potential health hazards associated with this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 133662-20-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,6,6 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 133662-20:
(8*1)+(7*3)+(6*3)+(5*6)+(4*6)+(3*2)+(2*2)+(1*0)=111
111 % 10 = 1
So 133662-20-1 is a valid CAS Registry Number.
133662-20-1Relevant articles and documents
Enantioselective Silver-Catalyzed Cascade Synthesis of Fused Lactone and Lactam Oxazolines
De La Campa, Raquel,Manzano, Rubén,Calleja, Paul,Ellis, Sam R.,Dixon, Darren J.
, p. 6033 - 6036 (2018)
A new and highly stereoselective cascade reaction between isocyanoacetate esters and α-hydroxy and α-amino ketones has been developed. A cinchona alkaloid derived aminophosphine/silver(I) catalyst complex promoted the reaction and enabled the ready synthesis of fused bicyclic γ-lactone and γ-lactam oxazolines with high enantiocontrol (up to 99% ee).
Palladium-Catalyzed [5 + 2] Annulation of Vinylethylene Carbonates with Barbiturate-Derived Alkenes
Chen, Yuehua,Deng, Hao,Gao, Xing,Guo, Hongchao,Jiang, Feng,Wang, Wei,Wu, Yongjun,Zhu, Dongyu
supporting information, p. 7158 - 7163 (2020/10/02)
A palladium/XantPhos-catalyzed [5 + 2] annulation of VECs with electron-deficient alkenes having an isolated carbon-carbon double bond has been developed to afford spirobarbiturate-tetrahydrooxepines. This study provides an expedient assembly of biologically interesting spirobarbiturate-tetrahydrooxepines. The easy scalability and versatile transformability of the reaction products were also exhibited.
Direct Aerobic Oxidative Reactions of 2-Hydroxyacetophenones
Sahoo, Subas Chandra,Nath, Utpal,Pan, Subhas Chandra
, p. 4434 - 4438 (2017/08/23)
Valuable and direct aerobic oxidation reactions of 2-hydroxyacetophenones were explored. The concept was based on the in situ treatment of small quantities of aerobically formed α-keto aldehydes that drove the reactions to the corresponding products. This new strategy was applied for a variety of oxidative reactions of 2-hydroxyacetophenones, and valuable products such as phthalides, quinoxalines, and α-keto amides were obtained in good to high yields.
