1337470-52-6 Usage
Description
(S)-(1,4-dioxan-2-yl)methanamine, also known by its IUPAC name (S)-2-(aminomethyl)-1,4-dioxane, is a chemical compound that features an amine group attached to a dioxane ring structure. This amine compound is characterized by its clear, colorless liquid appearance at room temperature. It is a versatile molecule with significant applications in the pharmaceutical and research sectors, particularly in the synthesis of organic compounds and the production of biologically active molecules.
Uses
Used in Pharmaceutical Industry:
(S)-(1,4-dioxan-2-yl)methanamine is used as a reagent for the synthesis of various organic compounds, playing a crucial role in the development of new drugs and pharmaceutical products. Its unique structure allows it to participate in a wide range of organic chemistry reactions, contributing to the creation of diverse molecular structures with potential therapeutic applications.
Used in Research and Development:
In the research industry, (S)-(1,4-dioxan-2-yl)methanamine serves as a chiral building block, which is essential for the production of biologically active molecules. Its ability to influence the stereochemistry of synthesized compounds makes it a valuable tool in the development of enantiomerically pure drugs, which can have significant implications for their efficacy and safety profiles.
Used as an Intermediate in Drug Manufacturing:
(S)-(1,4-dioxan-2-yl)methanamine is also employed as an intermediate in the manufacturing process of certain drugs and pharmaceutical products. Its presence in the synthesis pathway enables the production of complex molecular structures with specific therapeutic properties, ultimately contributing to the development of innovative treatments for various medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1337470-52-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,3,7,4,7 and 0 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1337470-52:
(9*1)+(8*3)+(7*3)+(6*7)+(5*4)+(4*7)+(3*0)+(2*5)+(1*2)=156
156 % 10 = 6
So 1337470-52-6 is a valid CAS Registry Number.
1337470-52-6Relevant articles and documents
CONDENSED HETEROCYCLES AS BCL-2 INHIBITORS
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, (2021/04/10)
The disclosure includes compounds of Formula (A) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11, h, j, m, n, k, v, s, g, V, W, L, Z1 Q1, Q2, Q3, Q4, Q5, Q6, and Q7, are defined herein. Also disclosed is a method for treating a neoplastic disease, an autoimmune disease, or a neorodegenerative disease with these compounds.
HOT MELT EXTRUDED SOLID DISPERSIONS CONTAINING A BCL2 INHIBITOR
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, (2021/09/04)
A pro-apoptotic solid dispersion comprises, a Bcl -2 family protein inhibitory compound of Formula A as defined herein, dispersed in a solid matrix that comprises (a) a pharmaceutically acceptable water-soluble polymeric carrier, and (b) a pharmaceutically acceptable surfactant. A process for preparing such a solid dispersion comprises subjecting to elevated temperature the compound of Formula A, the water-soluble polymeric carrier, and the surfactant to provide an extrudable semi-solid mixture; extruding the semi-solid mixture; and cooling the resulting extrudate to provide a solid matrix comprising the polymeric carrier, and the surfactant and having the compound dispersed in essentially non-crystalline form therein. The solid dispersion is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl -2 family proteins, for example cancer or an immune or autoimmune disease.
BCL-2 INHIBITORS
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, (2020/03/15)
The disclosure includes compounds of Formula (A), (A) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, and R11, h, j, m, n, k, v, s, g, V, W, L, Z1, Q1, Q2, Q3, Q4, Q5, Q6, and Q7, are defined herein. Also disclosed is a method for treating a neoplastic disease, an autoimmune disease, or a neorodegenerative disease with these compounds.
