1338058-47-1

Basic information

• Product Name: ethyl 4-(4-(benzylamino)-3-nitrophenyl)-3-methyl-4-oxo-butanoate
• Synonyms: ethyl 4-(4-(benzylamino)-3-nitrophenyl)-3-methyl-4-oxo-butanoate
• CAS NO: 1338058-47-1
• Molecular Weight: 370.405
• Mol File: 1338058-47-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 4-(4-(benzylamino)-3-nitrophenyl)-3-methyl-4-oxo-butanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 4-(4-(benzylamino)-3-nitrophenyl)-3-methyl-4-oxo-butanoate(1338058-47-1)
• EPA Substance Registry System: ethyl 4-(4-(benzylamino)-3-nitrophenyl)-3-methyl-4-oxo-butanoate(1338058-47-1)

Safety Data

• Hazardous Substances Data: 1338058-47-1(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 64-17-5 ethanol 
• 85633-97-2 4-(4-benzylamino-3-nitro-phenyl)-3-methyl-4-oxo-butyric acid 
• 85633-96-1 3-methyl-4-oxo-4-(3'-nitro-4'-chloro-phenyl)-butyric acid 

Downstream Products

• 118428-37-8 pimobendan 
• 136609-85-3 6-(3,4-diaminophenyl)-5-methyl-2,3,4,5-tetrahydropyridazin-3-one 
• 77469-62-6 5-methyl-6-[3'-nitro-4'-benzylamino-phenyl]-4,5-dihydro-3(2H)-pyridazinone 

Relevant articles and documents

PIMOBENDAN MANUFACTURING PROCESS

The present invention generally relates to an improved process for the manufacture of a non- solvated crystalline compound of formula (I). The invention further relates to a new valuable intermediate compound for the commercial synthesis of pimobendan, which is a compound according to formula (I) n MeOH, wherein n is from 1 to 2 molar equivalents. Still further, the invention relates to the use of said intermediate compound or a compound according to formula (I) obtained by the process of the invention, for the manufacture of a pharmaceutical composition.