133812-18-7

Basic information

• Product Name: 2-Oxazolidinone, 3-(1-oxo-3-phenyl-2-propenyl)-4-(phenylmethyl)-, (S)-
• CAS NO: 133812-18-7
• Molecular Formula: C19H17NO3
• Molecular Weight: 307.349
• Mol File: 133812-18-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Oxazolidinone, 3-(1-oxo-3-phenyl-2-propenyl)-4-(phenylmethyl)-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Oxazolidinone, 3-(1-oxo-3-phenyl-2-propenyl)-4-(phenylmethyl)-, (S)-(133812-18-7)
• EPA Substance Registry System: 2-Oxazolidinone, 3-(1-oxo-3-phenyl-2-propenyl)-4-(phenylmethyl)-, (S)-(133812-18-7)

Safety Data

• Hazardous Substances Data: 133812-18-7(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 137789-54-9 diethyl {2-[(4S)-4-benzyl-2-oxo-1,3-oxazolidin-3-yl]-2-oxoethyl}phosphonate 
• 90719-32-7 (S)-4-Benzyl-2-oxazolidinone 
• 102-92-1 cinnamoyl chloride 
• 621-82-9 Cinnamic acid 

Downstream Products

• 1351467-51-0 (2S,3S)-2-(2-(tert-butoxy)-2-oxoethyl)-3-phenylhex-5-enoic acid 
• 142078-08-8 (4S)-3-((3S)-3-phenylhex-5-enoyl)-4-benzyl-1,3-oxazolidin-2-one 
• 1351467-50-9 (3S,4S)-tert-butyl 3-((S)-4-benzyl-2-oxooxazolidine-3-carbonyl)-4-phenylhept-6-enoate 
• 136159-65-4 (S)-4-benzyl-3-(3-phenylpropanoyl)oxazolidin-2-one 
• 942220-63-5 1-tert-butyl-5-methyl (2S,3S,1'R,αS)-2-[1'-phenyl-1'-(N-benzyl-N-α-methylbenzylamino)methyl]-3-phenylpentanedioate 
• 717137-46-7 (4S,3'R,αS)-3-{3'-[N-benzyl-N-(α-methylbenzyl)amino]-3'-phenylpropanoyl}-4-benzyloxazolidin-2-one 
• 265669-72-5 tert-butyl (3R,αS)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate 
• 942220-68-0 tert-butyl (1'S,4''S,αR)-2-[1'-phenyl-1'-(N-benzyl-N-α-methylbenzylamino)methyl]-3-phenyl-5-oxo-5-(4''-benzyl-oxazolidin-2''-one-3''-yl)pentanoate 
• 151133-00-5 tert-butyl (3S,αR)-3-[N-benzyl-N-(α-methylbenzyl)amino]-3-phenylpropanoate 

Relevant articles and documents

Regio-selective reduction of the C-C double bonds in α,β- unsaturated acyl 4-substituted oxazolidin-2-ones and oxazolidine-2-thiones

Selective saturation of the conjugated C-C double bonds in the title compounds was examined in a systematic way for the first time. Many established protocols effective for similar reduction of α,β-unsaturated ketones and esters in the literature were found to be inapplicable in the present context. The most satisfactory results were finally obtained using the DIBAL-H/MeLi/CuI/HMPA/THF conditions.

DCC/DMAP-Mediated Coupling of Carboxylic Acids with Oxazolidinones and Thiazolidinethiones

Dicyclohexylcarbodiimide and catalytic dimethylaminopyridine were successfully used in the coupling of carboxylic acids with oxazolidinones and thiazolidinethiones. The acylated products were obtained in good yields.