133812-91-6

Basic information

• Product Name: <2S-(2a(S*),3aα,4β,7β,7aα)>-α-<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>benzolacetonitril
• Synonyms: <2S-(2a(S*),3aα,4β,7β,7aα)>-α-<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>benzolacetonitril
• CAS NO: 133812-91-6
• Molecular Weight: 311.424
• Mol File: 133812-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: <2S-(2a(S*),3aα,4β,7β,7aα)>-α-<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>benzolacetonitril(CAS DataBase Reference)
• NIST Chemistry Reference: <2S-(2a(S*),3aα,4β,7β,7aα)>-α-<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>benzolacetonitril(133812-91-6)
• EPA Substance Registry System: <2S-(2a(S*),3aα,4β,7β,7aα)>-α-<(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy>benzolacetonitril(133812-91-6)

Safety Data

• Hazardous Substances Data: 133812-91-6(Hazardous Substances Data)

Upstream product

• 532-28-5 (RS)-mandelonitrile 
• 108031-76-1 <2R-(2α,3aα,4β,7β,7aα)>-Octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-ol 

Downstream Products

• 3198-15-0 (1R,2S)-(-)-norephedrine hydrochloride 

Relevant articles and documents

Amino-Alcohols, I: A Method for the Synthesis of Enantiomerically Pure 1,2-Aminoalcohols with erythro-Configuration

The synthesis of both enantiomers of norephedrine and norisoephedrine is described to present a method for the preparation of enantiomerically pure branched 1,2-aminoalcohols.In a one pot reaction enantiomerically pure cyanohydrins bearing an acetal protective group are subjected to Grignard-reaction followed by addition of lithium aluminium hydride.After deprotection the target compounds are obtained.