133828-13-4Relevant articles and documents
POLYSUBSTITUTED 4-PIPERIDONES AND 4-PIPERIDOLS: SYNTHESIS AND SPATIAL CONFIGURATION
Belostotskii, A. M.,Shapiro, A. B.
, p. 421 - 429 (1991)
Triacetonamine was used to synthesize a series of highly substituted 4-piperidones and 4-piperidols.The spatial configuration of these compounds was determined.The anionoid addition to the carbonyl group of these piperidones proceeds through highly stereoselective equatorial attack.The position of the chair-chair-twist conformational equilibrium was determined for the polysubstituted 4-piperidols.