133832-78-7

Basic information

• Product Name: 3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-heptitol
• Synonyms: 3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-heptitol
• CAS NO: 133832-78-7
• Molecular Weight: 355.431
• Mol File: 133832-78-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-heptitol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-heptitol(133832-78-7)
• EPA Substance Registry System: 3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-heptitol(133832-78-7)

Safety Data

• Hazardous Substances Data: 133832-78-7(Hazardous Substances Data)

Upstream product

• 1100-88-5 benzyltriphenylphosphonium chloride 
• 133832-75-4 (E/Z)-3-(tert-Butoxycarbonylamino)-1,2,3-tridesoxy-1-phenyl-D-manno-hept-1-enitol 

Downstream Products

• 100564-78-1 (2R)-(tert-butoxycarbonylamino)-4-phenylbutanoic acid 

Relevant articles and documents

Synthesis of Chiral Building Blocks from D-Glucosamine Hydrochloride

Wittig-reaction of 2-acetamido-2-deoxy-D-glucose (1) with the semistabilized ylide Ph3P=CHPh yielded the epimeric chain-elongated derivatives 2 and 3 in different amounts depending on the reaction conditions.Reaction of 2-(tert-butoxycarbonylamino)-2-deoxy-D-glucose (5) with Ph3P=CHPh yielded the compound 8, or after intramolecular cyclisation, the derivatives 6 or 7.Compound 3 was transformed in three steps into the amino alcohol 10.The 3-amino-1,2-diol derivative 17 and also the N,O-protected α-hydroxy-β-amino acid derivative 16 were obtained from 7.The N-protected homophenylalanine derivatives 12 and 14 were available in two steps from 2 or 8. - Key Words: Amino sugars / Amino alcohols / Amino acids / Wittig reaction