1338456-40-8

Basic information

• Product Name: N-[3-(6-chlorocoumarin-4-ylmethoxy)phenyl]acetamide
• CAS NO: 1338456-40-8
• Molecular Weight: 343.766
• Mol File: 1338456-40-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-[3-(6-chlorocoumarin-4-ylmethoxy)phenyl]acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-[3-(6-chlorocoumarin-4-ylmethoxy)phenyl]acetamide(1338456-40-8)
• EPA Substance Registry System: N-[3-(6-chlorocoumarin-4-ylmethoxy)phenyl]acetamide(1338456-40-8)

Safety Data

• Hazardous Substances Data: 1338456-40-8(Hazardous Substances Data)

Upstream product

• 106-48-9 4-chloro-phenol 
• 79344-40-4 6-chloro-4-bromomethylcoumarin 
• 621-42-1 meta-hydroxyacetanilide 

Relevant articles and documents

Synthesis, antimicrobial and DNA cleavage studies of some 4-aryloxymethylcoumarins obtained by reaction of 4-bromomethylcoumarins with bidentate nucleophiles

Symmetrical bidentate nucleophiles such as resorcinol have been made to react with 4-bromomethylcoumarins in a cascaded manner to obtain mono and bis-4-aryloxymethylcoumarins by a room temperature allylic nucleophilic displacement. Unsymmetrical nucleophiles such as 3-acetylaminophenol and 3-diethylaminophenol have been used to generate 4-aryloxymethylcoumarins. All the compounds have been analyzed by spectralmethods and subjected to preliminary antibacterial, antifungal and DNA cleavage studies. The results showed that the compounds bearing methoxy, chloro and bromo substituents at C6-position of coumarin showed higher activity. Springer Science+Business Media, LLC 2011.