1338582-85-6Relevant articles and documents
Synthesis and in vitro activity of novel N-3 acylated TSAO-T compounds against HIV-1 and HCV
Moura, Marina,Josse, Solen,Van Nhien, Albert Nguyen,Fournier, Carole,Duverlie, Gilles,Castelain, Sandrine,Soriano, Elena,Marco-Contelles, José,Balzarini, Jan,Postel, Denis
, p. 5046 - 5056 (2011/11/30)
Preparation of a small library of derivatives of the potent HIV-1 Reverse Transcriptase inhibitor TSAO-T bearing mono or di-carbonyl substituents (designed after docking analysis) at position N-3 is reported. A one-pot synthetic methodology has been devel