1338716-19-0

Basic information

• Product Name: 5-amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(4-hydroxy-2-(trifluoromethyl)phenyl)thiazole-4-carboxamide
• Synonyms: 5-amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(4-hydroxy-2-(trifluoromethyl)phenyl)thiazole-4-carboxamide
• CAS NO: 1338716-19-0
• Molecular Weight: 495.528
• Mol File: 1338716-19-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(4-hydroxy-2-(trifluoromethyl)phenyl)thiazole-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(4-hydroxy-2-(trifluoromethyl)phenyl)thiazole-4-carboxamide(1338716-19-0)
• EPA Substance Registry System: 5-amino-N-(5-(4-(aminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(4-hydroxy-2-(trifluoromethyl)phenyl)thiazole-4-carboxamide(1338716-19-0)

Safety Data

• Hazardous Substances Data: 1338716-19-0(Hazardous Substances Data)

Upstream product

• 1338718-67-4 tert-butyl (1-(1-methyl-4-nitro-1H-pyrazol-5-yl)piperidin-4-yl)methylcarbamate 
• 1338718-66-3 tert-butyl (1-(4-amino-1-methyl-1H-pyrazol-5-yl)piperidin-4-yl)methylcarbamate 
• 943918-05-6 (4-hydroxy-2-(trifluoromethyl)phenyl)boronic acid 
• 1338718-68-5 tert-butyl 4-(5-(4-(butyloxycarbonylaminomethyl)piperidin-1-yl)-1-methyl-1H-pyrazol-4-ylcarbamoyl)-2-bromothiazol-5-ylcarbamate 

Relevant articles and documents

PYRAZOL-4-YL-HETEROCYCLYL-CARBOXAMIDE COMPOUNDS AND METHODS OF USE

Pyrazol-4-yl-heterocyclyl-carboxamide compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, wherein X is a thiazolyl, picolinyl, pyridinyl, or pyrimidinyl, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.