133891-87-9

Basic information

• Product Name: 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine
• Synonyms: 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine;1-Benzhydryl-3-Methylazetidin-3-yl Methanesulfonate;1-Benzhydryl-3-mesyloxy-3-methylazetidine;Methanesulfonic acid 1-benzhydryl-3-methyl-azetidin-3-yl ester;1-(Diphenylmethyl)-3-methyl-3-((methylsulfonyl)oxy)azetidine
• CAS NO: 133891-87-9
• Molecular Formula: C₁₈H₂₁NO₃S
• Molecular Weight: 331.42924
• Mol File: 133891-87-9.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine(133891-87-9)
• EPA Substance Registry System: 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine(133891-87-9)

Safety Data

• Hazardous Substances Data: 133891-87-9(Hazardous Substances Data)

Usage

Description

1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine is a chemical compound belonging to the azetidines class. It is a highly functionalized molecule characterized by the presence of a benzhydryl group, a methanesulfonyloxy group, and a methylazetidine group. The benzhydryl group features a central carbon atom connected to two phenyl groups, while the methanesulfonyloxy group consists of a sulfur atom bonded to two oxygen atoms and a methyl group. This unique structure and reactivity make 1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine a promising candidate for applications in organic synthesis and pharmaceutical research, as well as a potential building block for constructing more complex molecules with specific biological activities.

Uses

Used in Organic Synthesis:
1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure and reactivity allow for the formation of new chemical bonds and the synthesis of target compounds with desired properties.
Used in Pharmaceutical Research:
1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine is used as a starting material or building block in pharmaceutical research for the development of new drugs with specific biological activities. Its unique functional groups can be further modified or combined with other molecules to create novel drug candidates with potential therapeutic applications.
Used in the Construction of Complex Molecules:
1-Benzhydryl-3-methanesulfonyloxy-3-methylazetidine is used as a versatile building block for constructing more complex molecules with specific biological activities. Its unique structure and reactivity enable the formation of diverse molecular architectures, which can be further optimized for improved potency, selectivity, and pharmacokinetic properties.

Upstream product

• 40320-63-6 1-benzhydryl-3-methylazetidin-3-ol 
• 124-63-0 methanesulfonyl chloride 
• 133891-86-8 1-diphenylmethyl-3-hydroxy-3-methylazetidine hydrochloride 
• 40320-60-3 N-benzhydryl 3-azetidinone 

Downstream Products

• 133891-88-0 1-benzhydryl-3-methylazetidine-3-carbonitrile 
• 133891-61-9 3-(dimethylamino)-1-(diphenylmethyl)-3-methylazetidine 
• 133891-52-8 3-amino-1-(diphenylmethyl)-3-methylazetidine 
• 133891-60-8 1-(diphenylmethyl)-3-methyl-3-methylaminoazetidine 
• 133891-59-5 3-(aminoethyl)-1-(diphenylmethyl)-3-methylazetidine 
• 133891-58-4 1-(diphenylmethyl)-3-methyl-3-(((trifluoroacetyl)amino)methyl)azetidine 
• 1613720-40-3 6-(1-benzhydryl-3-methylazetidin-3-ylamino)-7-fluoro-4-methyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613720-21-0 6-(1-benzhydryl-3-methylazetidin-3-ylamino)-4-methyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613720-22-1 6-(1-benzhydryl-3-methylazetidin-3-ylamino)-7-bromo-4-methyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613720-23-2 6-(1-benzhydryl-3-methylazetidin-3-ylamino)-4-methyl-7-phenyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613720-50-5 6-(1-benzhydryl-3-methylazetidin-3-ylamino)-4,7-dimethyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613721-08-6 (R)-6-(1-benzhydryl-3-methylazetidin-3-ylamino)-4-methyl-2,10-dihydro-9-oxa-1,2,4a-triazaphenanthren-3-one 
• 1613720-05-0 2-[6-(1-benzhydryl-3-methylazetidin-3-yloxy)-3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl]propionic acid ethyl ester 
• 1613720-30-1 2-[7-fluoro-6-(1-benzhydryl-3-methylazetidin-3-yloxy)-3-oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl]propionic acid ethyl ester 

Relevant articles and documents

SUBSTITUTED PYRAZOLOPYRIMIDINES AS IRAK4 INHIBITORS

The present application relates to novel pyrazolopyrimidine derivatives for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases in humans and in animals, especially of proliferative disorders, autoimmune disorders, metabolic and inflammatory disorders characterized by an overreacting immune system, in particular rheumatological disorders, inflammatory skin disorders, cardiovascular disorders, lung disorders, eye disorders, neurological disorders, pain disorders and cancer, in human as well as of allergic and/or inflammatory diseases in animals, especially of atopic dermatitis and/or Flea Allergy Dermatitis, and especially in domestic animals, particularly in dogs.

The synthesis and biological evaluation of novel series of nitrile-containing fluoroquinolones as antibacterial agents

Several novel series of nitrile-containing fluoroquinolones with weakly basic amines are reported which have reduced potential for hERG (human ether-a-go-go gene) channel inhibition as measured by the dofetilide assay. The new fluoroquinolones are potent

QUINOLONE ANTIBACTERIAL AGENTS

Compounds of formula (I) wherein A is formula (II), formula (III) or formula (IV), and B is formula (V), formula (VI), or formula (VII), can be used in a variety of applications including use as antibacterial agents.