1338919-41-7

Basic information

• Product Name: (2R)-2-(1-methyl-5-(phenylcarbonyl)-1H-pyrrol-3-yl)-2-hydroxyacetic acid n-butyl ester
• CAS NO: 1338919-41-7
• Molecular Weight: 315.369
• Mol File: 1338919-41-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-2-(1-methyl-5-(phenylcarbonyl)-1H-pyrrol-3-yl)-2-hydroxyacetic acid n-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-(1-methyl-5-(phenylcarbonyl)-1H-pyrrol-3-yl)-2-hydroxyacetic acid n-butyl ester(1338919-41-7)
• EPA Substance Registry System: (2R)-2-(1-methyl-5-(phenylcarbonyl)-1H-pyrrol-3-yl)-2-hydroxyacetic acid n-butyl ester(1338919-41-7)

Safety Data

• Hazardous Substances Data: 1338919-41-7(Hazardous Substances Data)

Upstream product

• 344268-32-2 dibutyl tartrate 

Relevant articles and documents

Enantioselective Friedel-Crafts reaction of acylpyrroles with glyoxylates catalyzed by BINOL-Ti(IV) complexes

We report the first efficient enantioselective Friedel-Crafts hydroxyalkylation of pyrroles having one electron-withdrawing group at the α, β or N-positions with alkyl glyoxylates catalyzed by readily available chiral BINOL-Ti(IV) complexes (1-5 mol %). The reaction regioselectively led to the desired pyrrole-hydroxyacetic acid derivatives with good yields (70-96%) and enantiomeric excesses up to 96%, and is applicable in multigram scale with low loading of the catalyst (1 mol %).