1338924-35-8Relevant articles and documents
Synthesis and Antitumor Molecular Mechanism of Agents Based on Amino 2-(3',4',5'-Trimethoxybenzoyl)benzo[b]furan: Inhibition of Tubulin and Induction of Apoptosis
Romagnoli, Romeo,Baraldi, Pier Giovanni,Lopez-Cara, Carlota,Cruz-Lopez, Olga,Carrion, Maria Dora,KimatraiSalvador, Maria,Bermejo, Jaime,Estevez, Sara,Estevez, Francisco,Balzarini, Jan,Brancale, Andrea,Ricci, Antonio,Chen, Longchuan,Kim, Jae Gwan,Hamel, Ernest
experimental part, p. 1841 - 1853 (2012/06/04)
Induction of apoptosis is a promising strategy that could lead to the discovery of new molecules active in cancer chemotherapy. This property is generally observed when cells are treated with agents that target microtubules, dynamic structures that play a