1339804-14-6

Basic information

• Product Name: (1R,3S)-1,2,2-trimethylcyclopent-1,3-diyl (4R)-2-(3,3-difluoroprop-2-enyl)-4-phenyl-1,3,2-dioxaborolane
• Synonyms: (1R,3S)-1,2,2-trimethylcyclopent-1,3-diyl (4R)-2-(3,3-difluoroprop-2-enyl)-4-phenyl-1,3,2-dioxaborolane
• CAS NO: 1339804-14-6
• Molecular Weight: 332.198
• Mol File: 1339804-14-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1R,3S)-1,2,2-trimethylcyclopent-1,3-diyl (4R)-2-(3,3-difluoroprop-2-enyl)-4-phenyl-1,3,2-dioxaborolane(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3S)-1,2,2-trimethylcyclopent-1,3-diyl (4R)-2-(3,3-difluoroprop-2-enyl)-4-phenyl-1,3,2-dioxaborolane(1339804-14-6)
• EPA Substance Registry System: (1R,3S)-1,2,2-trimethylcyclopent-1,3-diyl (4R)-2-(3,3-difluoroprop-2-enyl)-4-phenyl-1,3,2-dioxaborolane(1339804-14-6)

Safety Data

• Hazardous Substances Data: 1339804-14-6(Hazardous Substances Data)

Upstream product

• 75-38-7 Vinylidene fluoride 
• 78315-30-7 2,2-difluoro vinyllithium 

Relevant articles and documents

B -(3,3-Difluoroallyl)diisopinocampheylborane for the enantioselective fluoroallylboration of aldehydes

The fluoroallylboration of aldehydes with B-(3,3-difluoroallyl) diisopinocampheylborane, which was prepared via the hydroboration of 1,1-difluoroallene, provides chiral 2,2-gem-difluorinated homoallylic alcohols in good yields and 91-97% ee.

Asymmetric fluoroallylboration of aldehydes

Contrary to previous reports, the homologation of benzyloxydifluorovinyllithium with bulky chiral iodomethylboronates readily provides a series of chiral γ,γ-difluoroallylboronates. Asymmetric fluoroallylboration of aldehydes with a 2-phenylbornane-2,3-diol-derived reagent provides gem-difluorinated homoallyl alcohols in good yields and 77-95% ee. Preparation of a chiral α-pyrone in >99% ee has also been described.