133992-80-0 Usage
Description
1-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYL)-PYRROLIDINE-2-CARBOXYLIC ACID is a chemical compound characterized by its molecular formula C9H11F3NO3. It is a pyrrolidine derivative that features a carboxylic acid functional group. 1-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYL)-PYRROLIDINE-2-CARBOXYLIC ACID is known for its unique chemical structure and properties, which make it a valuable asset in various fields.
Uses
Used in Chemical Research:
1-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYL)-PYRROLIDINE-2-CARBOXYLIC ACID is utilized as a key component in chemical research, where its distinctive properties contribute to the understanding of different chemical reactions and processes.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYL)-PYRROLIDINE-2-CARBOXYLIC ACID serves as a building block for the synthesis of various pharmaceuticals and bioactive compounds. Its unique structure allows for the development of new drugs with potential applications in treating a range of medical conditions and diseases.
Used in Material and Chemical Development:
1-(4,4,4-TRIFLUORO-3-OXO-BUT-1-ENYL)-PYRROLIDINE-2-CARBOXYLIC ACID is also employed in the development of new materials and chemicals for industrial purposes. Its versatile chemical properties make it a promising candidate for creating innovative products and solutions in various sectors.
Check Digit Verification of cas no
The CAS Registry Mumber 133992-80-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,3,9,9 and 2 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 133992-80:
(8*1)+(7*3)+(6*3)+(5*9)+(4*9)+(3*2)+(2*8)+(1*0)=150
150 % 10 = 0
So 133992-80-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H10F3NO3/c10-9(11,12)7(14)3-5-13-4-1-2-6(13)8(15)16/h3,5-6H,1-2,4H2,(H,15,16)/p-1/b5-3+/t6-/m0/s1
133992-80-0Relevant articles and documents
Synthesis of trifluoromethyl and trifluoroacetyl substituted dihydropyrrolizines and tetrahydroindolizines
Gerus, Igor I.,Klipkov, Anton A.,Rusanova, Julia A.,Sorochinsky, Alexander E.,Tarasenko, Karen V.
, (2020)
The trifluoroacetic anhydride promoted cyclization of enaminones derived from proline or pipecolic acid and β-ethoxyvinyl trifluoromethyl ketone was reinvestigated. An operationally simple procedure for the selective synthesis of bicyclic trifluoromethylated pyrroles and bicyclic pyrroles bearing trifluoromethyl and trifluoroacetyl groups on the pyrrole ring was developed. The mechanism of cyclization explaining the formation of bicyclic trifluoromethylpyrroles was discussed and previously described structures of the cyclization products were corrected.
4-Ethoxy-1,1,1-trifluoro-3-buten-2-one as a new protecting reagent in peptide synthesis
Gorbunova,Gerus,Galushko,Kukhar
, p. 207 - 209 (2007/10/02)
The 4,4,4-trifluoro-3-oxo-1-butenyl group is proposed as a suitable protecting group for the protection of the N-H terminal of amino acids in peptide synthesis. Amino acids react with 4-ethoxy-1,1,1-trifluoro-3-buten-2-one to give the N-protected amino acids, the protecting group can be removed by acidic hydrolysis. The formation of peptide bonds using on N-4,4,4-trifluoro-3-oxo-1-butenyl protected amino acids occurs without racemization.
