1339955-99-5

Basic information

• Product Name: 4-[6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl]piperazin-1-carboxylic acid benzyl ester
• Synonyms: 4-[6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl]piperazin-1-carboxylic acid benzyl ester
• CAS NO: 1339955-99-5
• Molecular Weight: 454.956
• Mol File: 1339955-99-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-[6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl]piperazin-1-carboxylic acid benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl]piperazin-1-carboxylic acid benzyl ester(1339955-99-5)
• EPA Substance Registry System: 4-[6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-3-yl]piperazin-1-carboxylic acid benzyl ester(1339955-99-5)

Safety Data

• Hazardous Substances Data: 1339955-99-5(Hazardous Substances Data)

Upstream product

• 698-25-9 6-chloro-1H-indazole 
• 31166-44-6 phenylmethyl 1-piperazinecarboxylate 
• 1339955-83-7 3-bromo-6-chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole 
• 110-87-2 3,4-dihydro-2H-pyran 
• 885521-34-6 3-bromo-6-chloro-1H-indazole 

Relevant articles and documents

Direct access to 3-aminoindazoles by Buchwald-Hartwig C-N coupling reaction

An efficient synthesis of various N-substituted 3-aminoindazoles using Buchwald-Hartwig C-N coupling reaction is described. Several parameters were varied, including the nature of the halogen atom and the protecting group of the starting materials, as well as the effects of the catalyst system, base, solvent, and reaction time. The efficiency of microwave versus conventional heating was also compared to test the outcome of the reaction. Thus, by applying this recent knowledge about metal-catalyzed aminations, an alternative for the direct synthesis of primary 3-aminoindazoles has been provided. Georg Thieme Verlag Stuttgart. New York.