134-29-2 Usage
Description
O-ANISIDINE HYDROCHLORIDE, also known as ortho-anisidine hydrochloride, is a gray-black crystalline solid or light gray powder that may be carcinogenic. It exists as ortho-, meta-, and para-isomers and has a characteristic amine (fishy) odor. This chemical compound is widely utilized in various industries due to its unique properties and applications.
Uses
Used in Dye and Pigment Production:
O-ANISIDINE HYDROCHLORIDE is used as a chemical intermediate for the production of numerous azo and triphenylmethane dyes and pigments. These include C.I. direct red 72, disperse orange 29, direct yellow 44, direct red 24, and acid red 4. Its role in the synthesis of these dyes and pigments is crucial for the coloration of various materials, such as textiles, plastics, and inks.
Used in Pharmaceutical Industry:
O-ANISIDINE HYDROCHLORIDE is used as a chemical intermediate in the production of pharmaceuticals, including the expectorant guaiacol. Guaiacol is a medication used to relieve cough and promote the expulsion of mucus from the respiratory tract. The compound's presence in the synthesis of guaiacol highlights its importance in the development of medications that improve human health.
Used in Corrosion Inhibition:
In the steel industry, O-ANISIDINE HYDROCHLORIDE serves as a corrosion inhibitor for steel. Its ability to prevent or slow down the corrosion process is vital in protecting steel structures from damage, extending their lifespan, and reducing maintenance costs.
Used in Polymercaptan Resins:
O-ANISIDINE HYDROCHLORIDE is used as an antioxidant for polymercaptan resins. Its antioxidant properties help prevent the degradation of these resins, which are used in various applications, such as adhesives, coatings, and sealants. By enhancing the stability and durability of polymercaptan resins, O-ANISIDINE HYDROCHLORIDE contributes to the overall performance and longevity of products that incorporate these resins.
Air & Water Reactions
Water soluble.
Reactivity Profile
O-ANISIDINE HYDROCHLORIDE reacts as an acid to neutralize bases. These neutralizations generate some heat, Usually does not react as either oxidizing agents or reducing agents but such behavior is not impossible. May catalyze organic reactions.
Fire Hazard
Flash point data for O-ANISIDINE HYDROCHLORIDE are not available; however, O-ANISIDINE HYDROCHLORIDE is probably combustible.
Safety Profile
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data.
Mutation data reported. When heated to
decomposition it emits very toxic fumes of
NOx and HCl.
Potential Exposure
Anisidines are used in the manufacture
of azo dyes; pharmaceuticals; textile-processing chemicals
Incompatibilities: Incompatible with oxidizers (chlorates,
nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions.
Keep away from alkaline materials, strong bases,
strong acids, oxoacids, epoxides. Attacks some coatings
and some forms of plastic and rubber.
Carcinogenicity
o-Anisidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity in experimental animals.
Shipping
UN2431 Anisidines, Hazard Class: 6.1; Labels:
6.1-Poisonous materials
Waste Disposal
Dissolve in combustible solvent
(alcohols, benzene, etc.) and spray solution into furnace
equipped with afterburner and scrubber, or burn spill
residue on sand and soda ash absorbent in a furnace.
Check Digit Verification of cas no
The CAS Registry Mumber 134-29-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 134-29:
(5*1)+(4*3)+(3*4)+(2*2)+(1*9)=42
42 % 10 = 2
So 134-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO/c1-9-7-5-3-2-4-6(7)8/h2-5H,8H2,1H3
134-29-2Relevant articles and documents
Deoxygenation of Nitrous Oxide and Nitro Compounds Using Bis(N-Heterocyclic Silylene)Amido Iron Complexes as Catalysts
Chen, Xi,Driess, Matthias,Du, Shaozhi,Mo, Zhenbo,Wang, Hao
supporting information, (2021/12/03)
Herein, we report the efficient degradation of N2O with a well-defined bis(silylene)amido iron complex as catalyst. The deoxygenation of N2O using the iron silanone complex 4 as a catalyst and pinacolborane (HBpin) as a sacrificial reagent proceeds smoothly at 50 °C to form N2, H2, and (pinB)2O. Mechanistic studies suggest that the iron–silicon cooperativity is the key to this catalytic transformation, which involves N2O activation, H atom transfer, H2 release and oxygenation of the boron sites. This approach has been further developed to enable catalytic reductions of nitro compounds, producing amino-boranes with good functional-group tolerance and excellent chemoselectivity.
The ortho effect on the acidic and alkaline hydrolysis of substituted formanilides
Desai, Salil Dileep,Kirsch, Lee E.
, p. 471 - 488 (2015/06/30)
The kinetics of formanilides hydrolysis were determined under first-order conditions in hydrochloric acid (0.01-8 M, 20-60°C) and in hydroxide solutions (0.01-3 M, 25 and 40°C). Under acidic conditions, second-order specific acid catalytic constants were used to construct Hammett plots. The ortho effect was analyzed using the Fujita-Nishioka method. In alkaline solutions, hydrolysis displayed both first- and second-order dependence in the hydroxide concentration. The specific base catalytic constants were used to construct Hammett plots. Ortho effects were evaluated for the first-order dependence on the hydroxide concentration. Formanilide hydrolyzes in acidic solutions by specific acid catalysis, and the kinetic study results were consistent with the AAC2 mechanism. Ortho substitution led to a decrease in the rates of reaction due to steric inhibition of resonance, retardation due to steric bulk, and through space interactions. The primary hydrolytic pathway in alkaline solutions was consistent with a modified BAC2 mechanism. The Hammett plots for hydrolysis of meta- and para-substituted formanilides in 0.10 M sodium hydroxide solutions did not show substituent effects; however, ortho substitution led to a decrease in rate constants proportional to the steric bulk of the substituent.
ORGANOARSENIC COMPOUNDS WITH AN As=N BOND. VI. PROPERTIES OF DIMERIC As,As,As-TRIPHENYLARSINE IMIDES. CRYSTAL AND MOLECULAR STRUCTURE OF THE PRODUCT OF THEIR HYDROLYSIS
Kokorev, G. I.,Litvinov, I. A.,Naumov, V. A.,Yambushev, F. D.
, p. 304 - 310 (2007/10/02)
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