134-91-8

Basic information

• Product Name: BIS(4-DIETHYLAMINOPHENYL)METHANOL
• Synonyms: B-DAM;BIS(4-DIETHYLAMINOPHENYL)METHANOL;4,4'-BIS(DIETHYLAMINO)BENZHYDROL;Bisdiethylaminophenylmethanol;4,4'-bis(diethylamino)benzhydryl alcohol;Ethylhydrol;4,4''-BIS(DIETHYLAMINO)BENZHYDROL (B-DAM);Bis[p-(diethylamino)phenyl]methanol
• CAS NO: 134-91-8
• Molecular Formula: C₂₁H₃₀N₂O
• Molecular Weight: 326.48
• EINECS: 205-162-8
• Product Categories: Intermediates of Dyes and Pigments
• Mol File: 134-91-8.mol
• Article Data: 5

Chemical Properties

• Melting Point: 82°C
• Boiling Point: 492 °C at 760 mmHg
• Flash Point: 239.5 °C
• Appearance: Off-white crystalline powder
• Density: 1.056 g/cm³
• Vapor Pressure: 1.7E-10mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: 0-10°C
• CAS DataBase Reference: BIS(4-DIETHYLAMINOPHENYL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(4-DIETHYLAMINOPHENYL)METHANOL(134-91-8)
• EPA Substance Registry System: BIS(4-DIETHYLAMINOPHENYL)METHANOL(134-91-8)

Safety Data

• Hazard Codes: Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36/37/39-36
• Hazardous Substances Data: 134-91-8(Hazardous Substances Data)

Usage

General Description

BIS(4-DIETHYLAMINOPHENYL)METHANOL is a chemical compound that belongs to the class of diarylmethanols, which are often used as intermediates in the synthesis of pharmaceuticals and other organic compounds. BIS(4-DIETHYLAMINOPHENYL)METHANOL is commonly used as a starting material in the production of various active pharmaceutical ingredients and as a reagent in organic chemical reactions. It is a white crystalline solid that is soluble in organic solvents and is known for its ability to act as a chiral ligand in asymmetric catalysis. BIS(4-DIETHYLAMINOPHENYL)METHANOL is also used in the preparation of other chiral compounds and has applications in the field of medicinal chemistry and drug development.

InChI:InChI=1/C21H30N2O/c1-5-22(6-2)19-13-9-17(10-14-19)21(24)18-11-15-20(16-12-18)23(7-3)8-4/h9-16,21,24H,5-8H2,1-4H3

Upstream product

• 90-93-7 4,4'-bis(diethylamino)benzophenone 
• 135-91-1 4-(4-(diethylamino)benzyl)-N,N-diethylbenzenamine 
• 64-19-7 acetic acid 
• 2052-06-4 4-bromo-N,N-diethylaniline 
• 120-21-8 4-Diethylaminobenzaldehyde 

Downstream Products

• 107572-88-3 4-(4,4'-bis-diethylamino-α-hydroxy-benzhydryl)-naphthalene-2,7-disulfonic acid 
• 60813-13-0 (4-diethylamino-2-methyl-phenyl)-bis-(4-diethylamino-phenyl)-methane 
• 93641-91-9 4-(4,4'-bis-diethylamino-benzhydryl)-phenol 
• 145494-12-8 C₃₃H₃₉N₅ 
• 145494-17-3 4,4'-bis(diethylamino)benzhydylanilin 
• 1220284-25-2 C₂₇H₃₈N₂O 
• 1616558-95-2 C₂₆H₃₂N₂S 
• 1616558-96-3 C₂₇H₃₂N₂OS 
• 149248-39-5 diethyl bis-(4-(diethylamino) phenyl)methylphosphonate 

Relevant articles and documents

Photo-induced phosphorus radical involved semipinacol rearrangement reaction: Highly synthesis of γ-oxo-phosphonates

Hydroxyphosphoric acids display the unique biological activities, and they have some attractive prospects as clinical drug moleculars. Herein, a new approach for the synthesis of γ-oxo-phosphonates (the precursor of hydroxyphosphoric acid) has been established through the semipinacol rearrangement tactic involved the photo-induced phosphorus radical process. Most important, this transformation is avoid of the external oxidants, and occurs very well under the sunlight irradiation, meanwhile the γ-oxo-phosphonate was easily derivatized to obtain γ-hydroxyphosphoric acid, thus highlights the synthesis value of this method.

Synthesis and optical nonlinear property of Y-type chromophores based on double-donor structures with excellent electro-optic activity

New Y-type chromophores FTC-yh1 and FTC-yh2 containing bis(N,N-diethyl) aniline as a novel electron-donor, thiophene as a π-conjugated bridge and tricyanofuran (TCF) as an acceptor have been synthesized and systematically investigated in this paper. Density functional theory (DFT) was used to calculate the HOMO-LUMO energy gaps and first-order hyperpolarizability (β) of these chromophores. These chromophores showed better thermal stability with their decomposition temperatures all above 240 °C. Most importantly, the high molecular hyperpolarizability of these chromophores can be effectively translated into large electro-optic (EO) coefficients (r33) in poled polymers. The doped film-A containing 25 wt% chromophore FTC-yh1 displayed a value of 149 pm V-1 at 1310 nm, and the doped film-B containing FTC-yh2 showed a value of 143 pm V-1 at the concentration of 25 wt%. These values are almost four times higher than the EO activity of usually reported traditional single (N,N-diethyl)aniline nonlinear optical (NLO) chromophores FTC. High r33 values indicated that the double donors of the bis(N,N-diethyl)aniline unit can efficiently improve the electron-donating ability and reduce intermolecular electrostatic interactions, thus enhancing the macroscopic EO activity. These properties, together with the good solubility, suggest the potential use of the new chromophores as advanced material devices.

Synthesis, Characterization and UV-Vis-spectral Behaviour of 4-Benzhydrylamino-substituted Azobenzenes

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